35348 results
The aim of the project is to improve adherence to inhaled corticosteroids in children with asthma by using a Real-Time Medication Monitoring system (RTMM) and SMS alerts and to study weather improved adherence has an effect on asthma control and…
The main objective is to develop an objective symptom profile of chronic neck pain patients which addresses more facets of the health problem, including sensorimotor dysfunction. The first stage is the establishment of an objective quantification of…
The primary objective of this study is to compare overall survival (OS) in patients with metastatic colorectal carcinoma (CRC) when treated with FOLFIRI in combination with placebo versus FOLFIRI in combination with ramucirumab DP.Secondary…
Primary: To investigate the effects of 300 mg aliskiren on albuminuria in patients with non-diabeticnephropathy treated with ramipril 10 mg and volume intervention.Secundary: Effects of ramipril and ramipril plus aliskiren. Effects on RAAS…
The aim of this study is to investigate the long-term outcomes in patients with BWS that have been surgically treated at our institution with the help of simple, non-invasive, objective study tools. We hope to gain valuable information regarding the…
The primairy objective of the trial is to determine the efficacy of BIBW 2992 plus weekly paclitaxel compared to the investigators choise of chemotherapy alone in patients with NSCLC stage IIIb or IV progressing after experiencing a benefit from…
The aim of this study is to assess differences between lean and morbidly obese subjects in gut permeability, gut microbiota and mucosal inflammation and to assess the effects of weight loss after sleeve gastrectomy on gut permeability, microbiota…
Primary Objective: To determine the local and peripheral immune response in diabetic pregnancies in comparison to healthy controls. Immune response will be measured by counting Th1/Th2-cells, Tregs, NK-cells, monocytes and granulocytes. Produced…
Primary objective:To study the Quick-DASH (Disabilities of the Arm, Shoulder, and Hand) scores, reflecting functional outcome and pain in patients who sustained a complex elbow dislocation and were treated with ORIF and/or arthroplasty and a hinged…
Primary :to determine whether concomitant administration of the study drug with food reduces within- and between-subject variability in exposure as measured by area under the plasma concentration-time course profile (AUC) and maximum observed plasma…
1. To evaluate the feasibility and safety of dynamic light application in an Intensive Care facility2. To study the effects of dynamic light application on the incidence of delirium, the number of ICU and hospital days and mortality in a mixed…
The primary endpoint is overall survival (OS) in patients with low hENT1 expression. Ifthe hENT1 expression data are available for analysis prior to randomizing 250 patientsthen an interim analysis for sample size re-estimation may be performed.
Before embarking on a study using MRDTI as sole test to manage clinically suspected UE-DVT, we need to perform a study to determine whether the test has the potential to be useful in patients with suspected UE-DVT. This study has the objective to…
The primary statistical objective of this study is to describe mean differences in corneal staining (type and area), for OPTI-FREE EverMoist Multi-Purpose Disinfecting Solution compared to baseline.
See above
Primary Objective: *To study differences in pulmonary function (i.e. increased airway resistance) one year after hospitalisation for RSV LRTD between mechanically ventilated and non-ventilated infantsSecondary Objectives: *To study…
The primary objective is to investigate if there are differences in the acute postprandial vasodilating effect between different protein sources and if these differences are associated with differences in the responses of vasodilating factors.…
Renal sympathetic denervation is currently introduced in the Erasmus Medical Center. Th objective of the current study is to 1) study the effectiveness and safety of renal sympathetic denervation in patient with treatment resistent hypertension. 2)…
The major objective of the present study is to examine the effects of dietary plant sterols and stanols on fasting serum concentrations of oxyphytosterols. The minor objective is to investigate the effects of these products on postprandial serum…
Primary objectiveTo compare the efficacy of adjuvant mitotane treatment vs observational follow-up only in prolonging recurrence free survival (RFS) in patients with ACC after complete resection and low-intermediate risk for disease recurrence.…