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Imlifidase treatment for acute inflammation in AQP4-IgG associated neuromyelitis optica spectrum disorder

To analyse in what proportion of NMOSD patients with an episode of acute inflammation circulating pathogenic anti-AQP4 IgG antibodies are depleted below detection limits, as measured with a state-of-the-arts cell-based assay, in the timeframe within…

A controlled, open-label post-authorisation efficacy and safety study in imlifidase desensitised kidney transplant patients with positive crossmatch against a deceased donor prior to imlifidase treatment, including non-comparative registry and concurrent reference cohorts

This study has been transitioned to CTIS with ID 2024-511810-18-00 check the CTIS register for the current data. Primary objective• To determine the 1-year graft failure-free survival in highly sensitised kidney transplant patients, pre-treated with…