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Effects of insomnia and chronic use of hypnotics on driving performance

Aim of the study is to investigate what the influence is of insomnia on driving performance and to what extent this influence is attenuated by the use of hypnotics. Therefore, over-the-road driving performance of treated and untreated patients…

Melatonin Against Temazepam in Comparing adverse events in vulnerable elderly Hospitalized patients with sleeping problems

Primary objective: To investigate whether either melatonin or temazepam is superior to placebo in improving subjective sleep quality and to investigate whether melatonin is non-inferior to temazepam in acute hospitalized older patients.Secondary…

Efficacy of Sodium Oxybate to promote sleep in the ICU: A randomized controlled trial

To evaluate the efficacy of sodium oxybate (SXB) as a medical intervention to treat disrupted night sleep in the ICU.