1689 results
Non-inferiority (defined as < 12.5% increase) of pooled buffy coat-derived PR platelet concentrates (PR-plasma-PCs) compared to plasma (plasma-PCs) in terms of clinical efficacy determined by WHO grade ≥ 2 bleeding complications.
1. Cysteine is an essential amino acid for newborn preterm infants; 2. Cysteine requirements change rapidly with postnatal age; 3. The change in cysteine requirement with age is based upon cystathionase activity; 4. Intestinal cystathionase activity…
We aim to test the accuracy of Western gastroenterologists in differentiating T1 CRCs from its precursor lesions and subsequently in estimating invasion depth
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We hypothesize that oral glucose intake and consequently the endogenous induced hyperinsulinemia will lead to insulin-induced microvascular dilatation in healthy normotensive subjects. Furthermore, we suggest that the insulin-mediated microvascular…
The self-help intervention Happy@Work will reduce symptoms of depression. The self-help intervention Happy@Work will be cost effective.
It is hypothesized that participants who received information about social modeling effects in the intervention group consume less (snack) food compared to participants in the control group.
Tray application of 0.12% chlorhexidine gel-toothpaste has more than 15% better effect on ¡®de novo¡¯ plaque accumulation compared to tray application of regular toothpaste in a 3 day non-brushing model.
The hypothesis is that repeated remote ischaemic postconditioning (by improving vascular, immune and anti-inflammatory pathways) will minimize infarct size and, subsequently, will improve clinical outcome in stroke patients.
Young people with a psychotic disorder have the same social goals as their healthy peers, but their social networks are smaller, they participate less often in leisure activities and are less successful in work and education. This impairment in…
We hypothesize that the new AFI-III system – compared to the conventional AFI-II – enhances the distinction between early neoplasia and inflammation in BO and thus reduces the amount of false positive lesions, allowing for targeted sampling and…
- The level of psychotic reactivity differs between psychotic trait, state, and illness groups - Psychotic reactivity is mediated by biological reactivity in terms of dopamine and cortisol reactivity - The level of psychotic reactivity is…
Simular outcomes in patients with 4 implants compared with patients with 6 implants with respects to peri-implant bone level stability
It is hypothesized that respiratory depression from the opioid oxycodone will increase with concomitant administration of alcohol. Furthermore it is hypothesized that the increase in respiratory depression is not only dependent on the dosage of…
- Six weeks of ESM combined with personalized feedback sessions, compared with treatment as usual (TAU), leads to a stronger reduction in fatigue symptoms (primary outcome clinical effectiveness). - This intervention also leads to improvements in…
To compare the resection speed of two different devices for removal of polyps (≥8mm - ≤20 mm) in terms of efficiency and complications.
The NTX intervention training leads to significant increase in both near and far transfer outcomes, in comparison with the effects of a training of an active control group.
We hypothesize that an initial CPAP level of 15 cmH2O followed by down titration to 8 cmH2O is better CPAP strategy for preterm infants at birth when compared to the currently used initial CPAP level of 5 cmH2O followed by up-titration to 8 cmH2O…
We want to test the hypothesis that internet based guided self-help is not more expensive and not less effective than usual care for patients with phobias.
It is expected that the add-on intervention will lead to a greater decrease in depressive symptoms than the control condition. Furthermore we expect that the add-on intervention will be cost-effective.