657 results
Hypothesis: Percutaneous nephrostomy is non inferior to retrograde double J catheter regarding time to clinical recovery. Secondly, patient reported outcome measures (PROMS) comparing treatment room and OR settings of drainage procedures will most…
Adequate perfusion of an adult-sized renal graft in children demands significant hemodynamic changes after transplantation (Tx). Suboptimal renal graft perfusion due to inadequate hemodynamic adaptation increases the risk of loss of renal graft mass…
Improve postoperative urine continence after prostatectomy for prostate cancer.
The aim of the current study is to:1. Determine the incidence of CIN after introduction of preventive measures.2. Describe changes in the course of biomarkers serum creatinine, microalbumin and microglobulin related to intravenous ICM administration…
The aim of the study is to investigate the changes in peritoneal endothelial glycocalyx in end-stage renal disease (ESRD), with the duration of peritoneal dialysis, and relate these changes to alterations in peritoneal transport and morphology.…
To compare the recurrence rate at 1 year following Narrow Band Imaging and TURB (Arm A) with White Light Trans Urethral Resection of Bladder cancer (TURB) (Arm B) in patients with bladder cancer (NMIBC).The purpose of this study is to investigate…
The central hypothesis of this project is that atorvastatin (added on standard antihypertensive treatment ARB) causes a substantial decrease in MSNA in hypertensive patients with CKD.
Primary objective:- to investigate the safety and tolerability after a single oral dose in healthy men and women of non-childbearing potential. Secondary objective:- to investigate the pharmacokinetic of a single oral dose in healthy men and women…
To investigate the incidence of CIN in three hospitals where patients are treatedaccording to the current guidelines, to identify the prediction risk factors and toobtain blood and urine samples that will allow future identification and evaluation…
The purpose of this trial is to demonstrate the superior efficacy of pudendal neuromodulation in treating patients with neurogenic overactive bladder, who have failed conservative treatment, in a randomized cross-over trial.Symptoms of urinary…
The effects of kidney transplantation on circadian rhythm. Focus on sleep and cardiometabolic risks.
Primary Objective: - What influence has kidney transplantation on (recovery of) melatonin production?Secondary Objective(s): - Is recovery of melatonin rhythm after kidney transplantation related to improvement of other circadian rhythms, e.g. body…
To evaluate the long-term safety and efficacy of two concentration-controlled everolimus regimen in de novo liver transplant recipients at Month 36 post-transplantation.
Primary objectivesThe primary objective of the study is demonstrate that at least one of the sotrastaurin treatment arms is non-inferior to the active control regimen myfortic + tacrolimus with respect to composite efficacy failure (treated BPAR of…
Main objective: To evaluate the outcomes of the PelFIs in patients with OAB; the relation to the clinical efficacy of antimuscarinic treatment and to hyperactivity of the pelvic floor muscles.Secondary objectives:• To asses the efficacy of…
We want to investigate if in critically ill patients use of LMWH is associated with stable plasma levels of anti-Xa activity. Furthermore, we want to investigate if GFR and circulation influence anti-Xa activity and which complications can occur.…
In this study we aim to investigate the long-term results of the prepuberal orchidopexie for the acquired undescended testis. The volume and location of the testis are primary outcome parameters that display the result. This information will…
1. To establish the prevalence and prognostic impact of HD-associated LV dysfunction; 2. To identify (clues to) mechanisms/ pathways that are pathophysiologically involved in HD-associated LV function.
To establish the safety and and tolerability and early efficacy of Alkaline phosphatase in the treatment of sepsis patients with renal failure.
Primary objective:Can a difference between the change in the perception of pain over time (0-60 minutes) between tramadol and butylscopolamine in renal colic be proven?Secundary objectives:- Can a difference in the decline in VAS-score over time (0-…
(1) to establish the effect of adding amiloride to lithium- treatment on the progression of renal insufficiency in patients with lithium- nephropathy (2) to answer the question whether adding amiloride to the use of lithium has the same effect as…