538 results
To study cognitive and behavioral outcome and resting-state dynamics in children with a history of perinatal asphyxia before and after the introduction of hyothermia and to compare these data with a group of controls.
Objectives.The primary aims of this multicenter randomized clinical trial (RCT) are threefold1. to investigate whether a structured assessment and treatment program of intensive, supervised pre-partum pelvic floor muscle group training (PFMGT)…
The FAST Therapy Trial is a prospective trial of patients with a new diagnosis of fetal SVA aimed to compare the impact of different perinatal treatment strategies from the time of SVA diagnosis to birth or death1) The primary outcome will be the…
Primary objective: To evaluate the effect of treatment with oral hypoglycemic agents (OHA) on the incidence of large-for-gestational-age (LGA) infants in women with GDM requiring medication, compared to insulin (INS) treatment.Secondary objectives:…
To evaluate whether cervical pessary can replace cervical cerclage in women with previous preterm birth and a short cervix or in women with a history of multiple preterm births in terms of effectiveness and costs
To assess the efficacy of the novel kit for the detection of PAMG-1 in the cervico-vaginal secretions of pregnant women with clinically intact membranes presenting with signs and symptoms of PTL in predicting time-to-delivery.
This study aims to compare two management strategies by an international randomized controlled trial: the first relies on the overall conclusion from the Eurofoetus trial and advocates immediate percutaneous fetoscopic surgery for all stages of TTTS…
Main objectieve of this study is if EMDR is an effective treatment for women with FoC. Our hypotheses are that in follow-up measurement compared to the pretreatment-measurement 1) WITHIN the treatment group there will be a decrease in the severity…
Primary objective: To identify those groups of pregnant patients, planned to undergo cesarean delivery, who are at risk to develop severe hypotension (defined as a decrease of at least15% from the baseline tension) based on their preoperative volume…
The primary aim of this study is to investigate if prophylactic pharmacotherapy peripartum is associated with a lower chance of relapse peripartum. In more detail, we will investigate if there is a difference in relapse between patients that used…
1. To investigate whether children exposed to lithium or antipsychotics in utero have subtle structural brain differences compared to non-exposed children at the age of 8-14 years old (primary objective).2. To investigate whether children exposed to…
We aim to compare the effectiveness of sildenafil versus placebo in achieving healthy perinatal survival, in women with singleton pregnancies with severe fetal growth restriction of placental origin.
In women with early, mild PPH (blood loss 500-750ml) we would like to establish whether restrictive resuscitation strategy reduces the progression to severe PPH (blood loss > 1000 ml) compared to care as usual
To test telemonitoring with wireless CTG and blood pressure devices as a novel obstetric care strategy compared to hospital admittance in high risk pregnancies who require daily monitoring. Primary outcome is safety of pregnancy outcome measured by…
OBJECTIVE: To compare, in women with acute severe hypertensive disorders, clinical effectiveness of labetalol and nifedipine.
We aim to examine the differences in response of hemodynamic and ventilatory parameters between women in their first trimester of pregnancy and non-pregnant women during a CPET.
To describe serial changes in diastolic and systolic myocardial performance by comprehensive echocardiographic assessment in neonates prior to, during, and after ECMO treatment and relate this to the course of PPHN.
The aim of this trial is to investigate whether fetoscopic laser surgery improves the outcome for TAPS twins as compared to the control group (standard care consisting of expectant management, IUT, preterm delivery). The hypothesis is that…
(1) Longitudinally describe the language and speech development in preterm children at 9 years of age. (2) Investigate whether these outcomes are related to a divergent development of neurological (language) system and (3) whether these language and…
To compare the currently used Friedman partogram (FP) to the newly developed SIMPLE partogram (SP), based on the normogram of the consortium on Safe Labor, for the diagnosis and treatment of non-progressing labour.