1330 results
n.v.t.
Primary Objective: To compare the composition and functionality of neonatal microbiome arising from mothers receiving antibiotic prophylaxis before skin incision with the microbiome of neonates born when antibiotics are given after umbilical cord…
To assess the efficacy, safety and cost-effectiveness of the CYP2C19 genotype guided antiplatelet treatment strategy, using clopidogrel or prasugrel/ticagrelor.
To establish one large overarching cohort including all types of SpA (both non-radiographic, radiographic axial SpA and peripheral SpA) regardless of the disease stage and treatment and to longitudinally asses several disease aspects of SpA. The…
PRIMARY* To demonstrate the non-inferiority of intravenous-to-oral antibiotic switch therapy in clinically stable neonates with probable bacterial infection compared to a complete course of intravenous antibiotic therapySECONDARY* To describe the…
The primary objective is to determine the efficacy of MagnetOs BCP granules in inducing adequate bone quantity and quality to support endosseous dental implants in the two-staged maxillary sinus floor augmentation procedure. Herein the treatment…
The purpose of this study is to analyse the effect on pain reduction of butylscopolamine in a continuous intravenous infusion compared to a placebo in patients with renal colics not responding to oral NSAIDs.
The primary objective of this prospective open label study is to assess the ability of vedolizumab to promote clinical, endoscopic and histological remission in patients with active UC in an 'early' and a 'late' disease…
In this study, we want to demonstrate that MPP is no less effective than MPP plus XRT.
Primary objective:- to compare the amount of contrast medium required to perform iliac/peripheral and EVAR procedures using the AlluraClarity control settings and the study settings, at similar procedure complexity, quantified as fluoro time, number…
This study aims to investigate, using a prospective, longitudinal outcome study design to assess the use of REGENOSS in attaining spinal fusion in patients requiring single-level or 2 level Posterior Interbody Fusion of the lower lumbar spine.See…
The main objective of this study is to determine differences in vaccine responses in the pre-elderly age group (50-65 years of age) to a primary immunization with vaccine antigens to which no or (very) low pre-vaccination antibody levels and memory…
The purpose of this study is to evaluate the effect of high dose RAS-antagonists and beta-blocker treatment for the primary prevention of cardiac events in a population of patients with Type 2 diabetes mellitus (T2DM) with no evidence of a…
The primary objective of this trial is to test the safety and efficacy of Perceval valve versus standard sutured stented bioprosthetic aortic valves among the intended trial population. The secondary objective is to compare all relevant device and…
The objective of this study is to assess if 1) by using the Arctic Sun® 5000 Temperature Management System occurrence of fever can be prevented and 2) patients treated with the Arctic Sun® 5000 Temperature Management System have a better recovery…
The aim of this study is to guide European PH-centers to become specialized centers for training in PH. This approach is in line with European PH-guidelines [12] which classified the exercise training in specialized centers with a closely monitored…
Primary objective: To study the pharmacokinetics of gentamicin, tobramycin, vancomycin and ciprofloxacin in morbidly obese patients and compare with normal weight patients. Secondary objectives: To assess the influence of covariates (such as TBW,…
In this study the best treatment of DSPS will be investigated by comparison of existing treatments. We will investigate is patients with ADHD and DSPS have less favorable blood values for biomarkers of chronic diseases in comparison with norm values…
The primary objective of the study is to evaluate the diagnostic accuracy of a CTEPH screening program based on the stratification score and the *rule out criteria*.To prospectively assess the feasibility and cost-effectiveness of the CTEPH…
To demonstrate the additive IOP lowering effect of SIMBRINZA (dosed BID) when added to DUOTRAV solution in subjects with open-angle glaucoma or ocular hypertension.