36849 results
Define reference values for gastric and oesophageal scintigraphy for post-bariatric surgery patients.
The primary objective:To identify fluid and radiological biomarkers, in IA carriers, AHD patients, and EoHD patients, that can be linked to clinical outcome measures. We aim to link longitudinal changes in these biomarkers to disease progression.…
This is a first-in-human Phase Ia/Ib, open-label, multicenter, dose-escalation study designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and preliminary anti-tumor activity of RO7502175 as a single…
To determine whether sensitivity towards NAC varies during different phases of the menstrual cycle in breast cancer patients.
To evaluate the influence of DSA monitoring, provided by the NarcotrendTM monitor, on the speed of emergence and recovery from GA.
The primary aim of this study is to evaluate 3 techniques (CEUS, 3D and SMI), that can perhaps improve the ultrasound assessment of GCA with regard to its diagnostic value when applied alone or in combination. The hypothesis is that the diagnostic…
The primary objective of the study is to compare the PFS of SPd versus EloPd in patients with MM who have received 1 to 4 prior anti-MM lines of therapy and never received pomalidomide, selinexor, or elotuzumab. Patients must have had prior…
The BeyeOMARKER study*s primary aim is to (1) provide proof-of-concept for blood-based biomarkers as a tool for minimally invasive early detection of AD pathology in a diverse population from an alternative clinically relevant setting. Secondly, we…
The overall aim is to unravel the (patho)physiological mechanisms and potential clinical benefits of a pre-specified early switch from controlled to assisted ventilation. The primary objective is to investigate the changes in regional lung stress…
This study has two parts. The main objective of part 1 (in vivo) is todetermine changes in markers of oxidative stress in exhaled breath as a result of different short term oxygenation strategies (liberal versus conservative) . The main objective of…
To study if an online brief CBT intervention is effective for anxiety and depression compared to care as usual (CAU) in patients with PCOS
: To investigate whether the omission of surgical gowns during CTR and TVR surgeries af-fects postoperative wound infections
The primary objective of this study is to investigate the feasibility of a multimodal prehabilitation programme consisting of MIET during neoadjuvant intravenous chemotherapy infusion, HITT and strength training during the last six weeks prior to…
To study the impact of addition of the GAAD score to imaging in patients with chronic liver disease eligible for HCC surveillance.
We want to show in the current pilot trial that the current market ready automated device is safe and effective to use in humans as the proof of principle prototype, as well as check the instructions for use (IFU).
To investigate the feasibility of Bergström needle biopsies of the vastus lateralis muscle, and NIRS measurements of the gastrocnemius muscle in post-ICU patients.
Primary objective: To assess the impact of acute laser treatment on muscle tissue mitochondrial respiration in vivo in healthy, young adults. Secondary objective: To assess the impact of acute laser treatment on muscle cellular energy, anabolic,…
The primary objective of this clinical feasibility study is to assess the overall diagnostic yield of the Investigational Device in comparison to standard care. The secondary objective is to assess the safety issues that possibly occur while using…
The aim of this research project is to assess the feasibility and acceptability of an adapted version of Group Interpersonal Therapy [IPT] for parents from refugee backgrounds in primary care in The Netherlands. Moreover, the potential effectiveness…
IVD1: The primary objective of this clinical performance study is to evaluate the effectiveness of the MyChoice® test in identifying HRRm or non-HRRm mCSPC patients as part of the enrolment criteria for EvoPAR-prostate01. This clinical performance…