Zoeken naar een onderzoek

Randomized controlled trial of the effects of cognitive behavioral therapy for insomnia on sleep, impulsivity and aggression in forensic psychiatric patients

Poor sleep is a potential risk factor for impulsive and aggressive behavior. Our hypothesis is that treatment of sleeping problems in forensic psychiatric patients ameliorates sleep and general psychopathology, and reduces impulsivity and aggression…

Management of the Obstructive Sleep Apnea-Hypopnea Syndrome: Oral Appliance versus Continuous Positive Airway Pressure Therapy.

Primary aim of the randomised trial is to elucidate the efficacy of, respectively, Oral Appliance (OA) and Continuous Positive Airway Pressure (CPAP) therapy in the management of the Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS). It is…

Can attention for itch stimuli be modified?

The primary hypothesis is that attentional bias modification (ABM) training towards and away from pictorial itch stimuli results in altered attention for pictorial itch stimuli. Secondarily, it will be explored whether attentional bias modification…

Critical Illness Polyneuromyopathy - The effect of electrical nerve stimulation.

Muscle weakness in patients admitted to the Intensive Care Unit lengthens duration of mechanical ventilation, weaning and hospital stay. One of the causes for muscle weakness is critical illness polyneuromyopathy (CIPM). The incidence of CIPM varies…

The “Together Happy!” (Samen Happie!) intervention to prevent obesity through parenting: A study among Dutch parents of infants

Overweight and childhood obesity are still serious health problems, especially among children from families with lower socio-economic status (SES). Current obesity prevention programs are often not focussed on children’s first years of life,…

Anesthetic techniques in injuries to the finger

A tampon after vaginal surgery: useful or superfluous?

1. Is there, by using a vaginal tampon, less postoperative bleeding?; 2. Are there, by using a vaginal tampon, less postoperative infections?; 3. Is the result of prolapse surgery negatively influenced by not using a vaginal tampon?; 4. What kind of…

StayFine RCT: app-based anxiety and depression relapse prevention in adolescents

A guided app-based modular intervention (monitoring + intervention) is more effective than monitoring only in preventing relapse of anxiety and/or depression (in terms of time to relapse) in recovered youth aged 13 – 21 years up to three years…

SMOK-study:
SSRI Medication in pregnant women: Effect on development of children.

Regarding the facts that in the fetus serotonin is involved in the synthesis of serotonergic neurons (autoregulation) as well as in the development of target tissues such as specific parts of the brain, the use of SSRI (selective serotonin reuptake…

Effect of early biventricular pacing on long-term left ventricular remodeling in patients with acute myocardial infarction (RESCUE-MI).

Large myocardial infarction (MI) often results in left ventricular (LV) remodelling which is associated with an adverse long-term prognosis. Early biventricular pacing after acute MI may attenuate LV remodeling and may thereby lead to better…

The use of handheld reflectance confocal microscopy in the surgical treamtent of lentigo maligna

The aim of this study is to evaluate the efficacy of HH-RCM in the presurgical margin delineation for LM treated by conventional surgical excision.

Real world data collection and population-based analysis of incidence of patients with acute myeloid leukemia (AML).

The hypothesis: the overall survival of AML patients is influenced by AML type, age, genetic aberrancies, comorbidity and performance status of the patient as well as type of treatment.

In Vivo Straylight of Clareon/Vivinex IOLs

To explore the amount of straylight in patients implanted with a Clareon monofocal IOL in one eye and a Vivinex XY1 monofocal IOL in the other eye and compare these straylight values to those in the normal pseudophakic eye (i.e., the pseudophakic…

Patient Reported Outcomes in Charnley’s Hip Replacement Arthroplasty.

The objective of this study is to assess which Patient Reported Outcomes are used in follow-up studies of Charnley’s Hip Replacement Arthroplasty and to assess the prevalence of reporting Patient Reporting Outcomes in time.

Immunogenicity and adjuvant effect of the whole cell Pertussis component of the Dutch combined Diphtheria, Tetanus, Pertussis, Poliomyelitis ~ Haemophilus influenzae type b vaccine in infants compared to the old whole cell P vaccine and a new acellular P vaccine component.

To compare the immunogenicity of the whole cell versus the acellular pertussis component of the DTP IPV-Hib vaccine as measured by the antibody titers at 11 months before the 4th vaccination and at 12 months.

Uit balans

According to the current Dutch guidelines it is advised to train task-specific and goal-driven with stroke patients. This shows to be almost impossible with a lot of stroke patients in the early subacute phase, especially with the severely affected…

Clinical outcomes of patients with severe intestinal failure on intravenous nutrition at home.

To highlight the efficacy and safety of long-term use of olive-oil-based home parenteral nutrition in patients with severe intestinal failure

Het effect van koude op post-prandiaal triglyceride metabolisme

1. During cold exposure, we aim to stimulate (lipid) metabolism of BAT and muscle tissue. During this cooling process we will perform a two meal test to study the effect of cold exposure on triglyceride metabolism. 2. We expect that after cold…

Shared decision making in Perihilar Cholangiocarcinoma and Hepatocellular Adenoma: The SAPACHA study

The implementation of decision support tools (DCTs) will improve the level of shared decision making in patients with perihilar cholangiocarcinoma and hepatocellular adenoma

Recovery of walking ability using a robotic device.

The general hypothesis of the study is that robot-assisted treadmill training with will lead to greater improvements of functional outcome measures of gait performance, social participation and quality of life in stroke patients than the regular…