9822 resultaten
Several investigators have suggested using dietary carbohydrate restriction as a therapeutic strategy to allow the host to successfully compete against a tumor [2, 7, 19]. The induced ketosis and increased lipolysis after low carbohydrate diets have…
A higher percentage of patients with MRD levels <0.1% (MRD negativity) after up to 2 courses of induction chemotherapy plus quizartinib, as measured in the bone marrow using MFCM before start of consolidation therapy, compared to a historical…
The use of videoglasses will lead to more anxiety reduction than hearing preferred audio in patients undergoing surgical procedures under local anesthesia.
By measuring biomedical variables, such as movement, temperature, heart rate variability, blood volume pulse and skin conductance, by means of a wearable (wristband), stress-related parameters can be measured easily and continuously. It is…
Chronic heart failure (CHF) is a clinical syndrome resulting from a decreased cardiac output, insufficient to maintain adequate tissue oxygenation. Eventually, inadequate tissue oxygenation will lead to pathological alterations, especially at the…
Since progression from NAFLD to NASH is associated with significantly increased risk of morbidity and mortality, there is a clinical imperative to identify the NAFLD patients that rapidly progress to NASH from those who will remain in the NAFLD…
It is expected that the respiratory microbiome will be relatively stable over time in non-infectious patients.
OR workflow for surgeons needing to interact with the laparoscopic equipment during surgery is optimized using TedCube© in combination with the Myo™ gesture control armband and/or a wireless headset.
Blue light glasses can manipulate (i.e., inhibite) body melatonine production to re-adjust the circadian rhythm of shift workers, thereby having the potential to enhance viglance, cognitive function, and positive mood during night shift work.
The purpose of this study is to demonstrate the added value of using 'LMA-S in the ambulance with CPR in the Netherlands indigent patients. The hypothesis is that the value of using the LMA-S is located in the safety and speed of placing the…
To determine the epidemiology, diagnosis and prognosis of enterovirus (EV) and parechovirus (HPeV) infection in Dutch children. Hypotheses: 1. EVs are one of the most important viral agents of infection in Dutch children; 2. EVs are the major cause…
Conditioning with hydrocortisone will result in altered endogenous cortisol during rest in the evocation phase.
It is expected that the CFS patient gets more insight in his or her physical activity pattern, intentions develops to change the behaviour, and really changes the behaviour resulting in a reduction of the CFS complaints.
Does suppletion of vitamine D3 (cholecalciferol) have an effect on the systolic blood pressure in hypertensive, vitamin D insufficient patients? 1. H0 hypothesis: there is no effect on the systolic blood pressure; 2. H1 hypothesis: the systolic…
We hypothesise that an anti-inflammatory dietary pattern (AIDP) has a beneficial effect on gut microbiome (diversity and permeability), thereby improving global functioning (measured with Outcome Questionnaire 45, OQ-45), and health of patients with…
A single PRP injection result in a clinical relevant reduction of the complaints at six months, compared to an injection with saline.
We expect that the development of mitochondrial dysfunction lags behind the development of the hypermetabolic inflammatory state. Additionally, we hypothesize that the aggravation of factors related to the hypermetabolic inflammatory status, such as…
It is the aim of this study to establish an integrated risk profile including clinical risk factors, AF recurrence patterns, anatomical and electrophysiological characteristics, circulating biomarkers and individual genetic background, to predict…
fetal heart deformation and its development throughout pregnancy can be measured by speckle tracking. Fetal heart deformation might be different in pregnancies complicated by placental dysfunction.
The study of determinants of cardiovascular disease (CVD) is important because it provides insight in risks and opportunities to reduce the burden of CVD. A major gap in our current knowledge about CVD lies in the way we measure these determinants,…