2623 resultaten
We hypothesize that the underlying mechanisms of the varying response in multiple parameters within an individual can be attributed to variability in the causal path between drug administration, drug tissue distribution, and tissue receptor…
"Het primaire doel van het onderzoek is het evalueren van de fixatie en migratie patronen van de Persona Partial Knee (Zimmer Biomet, Warsaw, IN) in vivo, met model-based RSA. Het secundaire doel van het onderzoek is het analyseren van de korte…
Dental caries lesions (with ICDAS Codes 3 and 4) can be treated by sealing, offering a less invasive and less costly treatment option with the same results as preparation and restoration of the carious lesions.
Freezing of gait (FOG) is a particularly disturbing and potentially harmful symptom occurring in a majority of people with Parkinson's Disease (PD) over the course of disease. External cues, such as a metronome or bars on the floor, aid in…
Repetitive ePIPAC-OX as a palliative monotherapy is a feasible, safe, tolerable, and potentially effective treatment for isolated unresectable colorectal peritioneal metastases, with low and predictable costs and a low systemic uptake of oxaliplatin…
Providing vascular surgical patients and vascular surgeons with decision support tools will improve the level of shared decision-making during consultation, increase disease-specific knowledge and quality of life and decrease decisional conflict.
We hypothesize that aromatase-inhibitors will have lower efficacies in the presence of an abundant estrobolome and high ß-glucuronidase activity. It’s also unclear whether microbiota influences intestinal absorption of tamoxifen’s related metabolite…
the correspondence between orosensation of sweetness and post-oral sensation of calories influences resting energy expenditure, cerebral blood flow and gastric emptying, and more specifically that the “not sweet enough” beverage, that contains more…
The aims of the study are: To investigate the short-term effectiveness of antecedent and consequent behavioral teacher training techniques for teachers of children attending regular primary school (class 3 to 8, six to thirteen years old) with (…
We hypothesize that a certain shear load threshold exists, where an increase in the cytokine IL-1a is observed.
KNLTB TennisReady leads to less injuries then current warm up practice of tennisplayers.
In the Netherlands, 90% of the patients with gout are managed by general practitioners but most research has been done in secondary care. In primary care there are questions on the clinical relevance of long-term uric acid lowering treatment of gout…
We hypothesize that evaluation of the iCHEC bleeding questionnaire will result in a more accurate diagnostic screening tool for children who are suspected for a bleeding disorder
Primary hypotheses: 1a. Striatal [18F]DOPA influx (Ki) values in non-psychotic individuals with ASD are positively related to the total score on the UCLA Loneliness Scale (as an approximate measure of social defeat). 1b. Non-psychotic individuals…
It is hypothesized that the ingestion of plant based proteins will result in a similar muscle protein synthetic response compared to animal based proteins.
Cabazitaxel is a tubulin-binding taxane drug that improves survival of patients with docetaxel-metastatic-castration-resistant prostate cancer (mCRPC). Unfortunately, cabazitaxel is not effective in all patients and can have serious side effects.…
The Untire app will create awareness by proving psycho-education and will give insight in ones’ energy levels, ones’ thoughts and behaviors in relation to energy levels and provides exercises that help users to challenge ineffective thoughts and…
The effects of a brief compassion induction exercise will be compared to the effects of a neutral exercise. We hypothesize that a brief compassion induction in a sample of patients with PD will facilitate the choice of more adaptive emotion…
We expect to detect testosterone effects on response to exposure in terms of subjective anxiety and self reported social anxiety symptoms. Additionally we expect testosterone effects on implicit avoidance tendencies. Lastly, Personality traits,…