35181 resultaten
There is underdiagnosis of COPD. To solve this problem, we want to check healthy persons after a questionnaire on high risk of COPD.
The hypotheses is that image guided hybrid hyper-fractionated dose escalation with mucosal sparing proton therapy is a feasible and safe treatment for Locally Advanced Head and Neck Cancer patients.
1) How effective is being kind to other people in general compared to being kind to family/friends or being kind to strangers on the level of mental well-being? 2) How effective are the three variants of acts of kindness on improving positive…
Single-dose rifampicin has been shown to prevent 56% of incident cases of leprosy in the first two years, when given to contacts of newly diagnosed cases. Immunization of contacts with BCG has been less well documented, but appears to have a…
mainstreaming of germline genetic tests in regular healthcare is feasible for non-genetic healthcare professionals and acceptable for both patients and healthcare professionals
A novel, home-based, goal-orientated exercise program for patients with combined chronic cardiac and pulmonary disease is feasible and safe.
Co-infection with either HIV or malaria may have a major impact on the immune response during bacterial sepsis. Current knowledge on the pathogenesis of sepsis indicates an unbalanced response to infection characterized by both excessive pro-…
The current study focusses on 1) transfer of a skill trained in two virtual environments with different feedback on actual performance to performance with a myoelectrically controlled hand prosthesis, 2) comparing the ability of switching with the…
A cognitive behaviour intervention is more effective in achieving behavioural changes and therefore changes in lifestyle and cardiovascular risk profile than usual care in patients with type 2 diabetes.
Comparison of pharmacokinetics, pharmacodynamics, efficacy and safety of recombinant asparaginase(ASNase) versus Asparaginase medac during induction treatment in children with de novo ALL and to demonstrate that any clinical important difference to…
The development of a dry powder inhaler (DPI) that suits the needs of Parkinson’s patients, based on their inspiratory capacities, is essential. In this study, we will investigate the applicability of dry powder inhalation in Parkinson’s patients,…
This study hypothesizes that doxapram will protect preterm infants from both invasive ventilation (and related lung disease) and apnea of prematurity related hypoxia (and related impaired brain development).
Not applicable
Participation in supportgroups leads to an improvement in quality of life, social support, social network, self-efficacy and self-esteem.
The study hypothesis is that adjunctive antibiotic therapy will improve clinical response to standard of care (SOC) induction therapy in a subgroup of CD patients with a relapse-associated microbiome profile.
The aim of this randomized controlled study is to find a difference in clinical AASV recurrence with neoreflux at 1 and 2 years follow-up after Laser crossectomy in comparison with usual EVLA using a 1470 nm radial two rings fibre. (Biolitec)
SCH 351125 50 mg BID 2/days is an effective treatment for RA.
In this observational trial we would like to study the possible correlation between the probe-drug dextromethrophan and tamoxifen pharmacokinetics. In case a good correlation is available, this might help in a stepwise development of truly…
Health outcome indicators of parents and children in Northern Wijchen have improved in the period 2017-2019.
Primary: 1) Prospective evaluation of scheduled/elective care for patients suspected for DVT in terms of patients’ and physicians satisfaction (PROMs and PREMs) and waiting hours for the patients. 2) To evaluate whether oral administration of…