32597 resultaten
The actual ERAS statement regarding intra- and postoperative analgesia recommends to not use thoracic epidural catheters in laparoscopic surgery anymore as a gold standard. This cohort study will investigate an alternative possibility of pain…
1. There are differences of thermoregulatory behavior and thermo-physiology between healthy lean and obese subjects. 2. Healthy lean and obese individuals can be classified based on individual thermal preference, which is a result of distinct…
The amount of skin tension and the direction of highest skin tension is influenced by posture changes and the location of the body.
The main objective of the present study is to evaluate (cost)effectiveness of Dementia Care Mapping (DCM)intervention in nursing home dementia care by performing a large RCT study.
MMR vaccine administered intramuscularly induces the same adverse effects and immunogenicity as subcutaneously.
We hypothesize that the Ketogenic diet will be cost-effective compared to usual care.
Stabilisation of preterm infants performing physioloigcal based cord clamping using the Concord is at least as effective as stabilisation according to the standard approach using the standard resusciation table.
We hypothesise that there would be no significant difference between the preoperative planning between different orthopedic surgeons.
To assess the outcomes of endoscopic hernia repair (TEP) after implantation of a lightweight mesh (Ultrapro) versus a heavyweight mesh (Prolene). The hypothesis is that an endoscopic hernia repair with implantation of a lightweight mesh results in…
To compare a ventilation strategy that uses conservative targets (PaO2 55-80 mmHg (7.3-10.7 kPa)) with one that uses conventional oxygenation targets (PaO2 110-150 mmHg (14.7-20 kPa)) for arterial oxygenation. Primary endpoint is all-cause mortality…
Operative treatment with additional concentrated bone marrow cells results in better fifth metatarsal stress fracture healing than operative treatment alone. We furthermore hypothesize that composition of bone marrow cells also contributes to…
It is hypothesized that CATs and PROMIS short-forms have higher measurement precision and smaller measurement error (better detectable change) as compared to currently used PROMs.
1. Gatekeeper training is effective in enhancing relevant skills 2. Gatekeeper training will diminish rates of (attempted) suicides at regional level 3. The intervention is cost-effective relative to routine medical care
The Trammpolin® medial meniscus prosthesis is intended to restore the function of the natural meniscus to provide unicompartmental pain relief in the meniscus-deficient knee and redistributes the loads transmitted across the knee joint. The ability…
The Trachospray device gives complete anesthesia of the airway
1. Daily home monitoring of exhaled nitric oxide (FENO) in patients with severe asthma facilitate tapering of oral corticosteroids to the lowest possible dose, leading to a reduction of total corticosteroid consumption; 2. This can be achieved…
1. What is the effect of active patient involvement by the practice nurse on decisions regarding cardiovascular risk reduction, adherence to lifestyle advice, cardiovascular risk and other outcomes at 12 weeks and 52 weeks, compared to usual care?…
Rituximab treatment leads to a decrease in synovial B cells. The clinical response is related to the decrease in synovial B cell numbers.
We hypothesize that more participants in the experimental condition, who are offered the computer-tailored feedback program, will quit smoking and that these participants will become more physically active compared to the participants in the control…
It is hypothesized that measurement of CO, SV and LVEF with the Lumify/DIA system corresponds with CO, SV and LVEF measurements with conventional non-automated echocardiography.