4238 resultaten
The following hypotheses will be examined: a. patients with multiple sclerosis who become cognitively impaired may experience an increase in pain experience (due to white matter lesions) b. hyperesthesia is known to be predictive of central…
We hypothesize that ingestion of potato protein increases muscle protein synthesis rates at rest as well as during recovery from exercise in young healthy males. We hypothesize that the muscle protein synthetic response to the ingestion of potato…
This study aims to implement and evaluate an advance care planning (ACP) intervention for elderly nursing home patients with a limited life expectancy. The intervention consists of ACP discussions integrated with a structured multidisciplinary…
The main hypothesis is that use of Oncokompas will be superior to care as usual to reduce caregiver burden and to improve self-efficacy and quality of life, and it is expected that Oncokompas will improve quality-adjusted life years (QALYs) at…
We hypothesize that there is no difference in clinical and radiological outcome when using PSG for UKA compared with results from the literature describing results from conventional UKA surgical techniques.
The primary hypothesis is that the effect of tubal flushing with oil-based contrast results in higher ongoing pregnancy rates compared to water-based contrast medium.
The aim of this study is to develop and evaluate a health behavior change and social network enhancement intervention for low-income households in Apeldoorn who receive care for multiple problems (such as financial debts, domestic violence,…
screening for cardiovascular diseases will reduce coronary heart disease-related mortality and morbidity
We hypothesize that increased disease activity (i.e. more inflammation) is associated with an increased risk of developing ID.
Hypothesis 1: Participants in both conditions (experimental and placebo) will show a reduction in gamble problem severity immediately post-intervention and at 3-and 6-month follow-ups. However, participants in the experimental condition will show a…
To develop a dosing nomogram of irinotecan in patients homozygous polymorphic for UGT1A1*28 and/or UGT1A1*93 in order to reduce the incidence of severe irinotecan-associated toxicity, defined as febrile neutropenia in the first 2 cycles (amendment…
The gastric balloons are expected to remain in the stomach for approximately four weeks, after which they burst and are fecally excreted. It is further hypothesised that intragastric balloons can provide a surrogate stomach fill, inducing an…
A combination therapy (MDT and TESIs) is effective and cost-effective compared to usual care among herniated nucleus pulpos patients with an indication for a lumbar herniated disc surgery
Trends in and variability of vital signs reveal hidden information about the state and deterioration of the patient compared to absolute values of vital signs.
In the proposed study we will investigate the effect
Infant formulae with higher levels of milk fat result in improved fatty acids absorption as compared to standard formula.
Acid-reducing drugs, such as PPIs, may profoundly decrease solubility and, as a result, (negatively) affect the bioavailability of afatinib. Since a PPI is often used concomitantly during afatinib therapy, this DDI confronts physicians, patients,…
Structured cultural sensitive pre-Ramadan education helps people with diabetes who choose to participate in Ramadan fasting to experience a safer Ramadan period. Pre-Ramadan education reduces the risk of acute complications such as hypoglycemia. The…
The objective is to investigate whether application of a stepwise work-up strategy in primary care patients with uncontrolled hypertension results in better blood pressure control in a cost-effective manner.
The hypothesis of this study is that a difference in mental well-being can be observed after insertion of an LNG-IUD compared to Cu-IUD insertion.