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Pelvic floor muscle spasms resulting in chronic pelvic pain may occur as a primary event or secondary to a physical, psychological or pathological factor. First-line treatment consists of pelvic floor physiotherapy. When first-line treatment fails,…
1. We first propose that in advanced TC, not only tumor-associated macrophages (TAMs), but also circulating monocytes and bone marrow (BM) myeloid progenitors are functionally reprogrammed by tumor-derived metabolites even before their recruitment…
Patients undergoing superior capsule reconstructions (SCR) for superior shoulder instability will experience less pain (decrease of at least 2 points) and improved function.
1) Epidemiology of postoperative pain What is the correlation between pain intensity scores and type of surgical procedure in relation to patient characteristics and analgesia? Is it possible to specify surgical procedures indicating its pain…
It is hypothesized that SADI after sleeve gastrectomy for additional weight loss is superior to a gastric bypass as secondary procedure
PPIs are prescribed very frequently and might cause potentially severe hypomagnesaemia. We carried out a study focussing on the prevalence of hypomagnesaemia in geriatric inpatients using PPI and evaluated risk factors contributing to this effect.…
1, the effect of SLT diminishes in time; how fast does IOP get below target IOP after SLT? 2, is a repeat SLT effective to get/keep IOP under target IOP? 3, is there a racial difference in effect of SLT?
The bony-bridging-score is feasible to use to asses bon ingrowth on a CT-scan at 1 year follow up after postero lateral interbody fusion (PLIF) surgery. the degree of radiological bone ingrowth in patients who are eligible for a lumbar spinal…
ADMA (asymmetric dimethylarginine) plasma concentrations are higher in persons with mild renal insufficiency compared to persons with normal kidney function. ADMA plasma concentrations are inversely proportional to renal perfusion and endothelial…
Lithium treatment potentially enhances survival and slows disease progression in ALS patients
1) Product sales of specific products will increase during phases in which these products are nudged. 2) The effect of nudges on product sales (hypothesis 1) persists in the long-term, without active control of the experimenter. 3) Participants in…
To determine the effect of protocolled practice nurse-led asthma care for children aged 6 to 12 years old in primary care on asthma control (compared to usual care)
Evaluation of daily practice, improve quality of care to patients with spondyloarthritis
High-intensity stress reduces cognitive performance (visuo-spatial learning) both for immediate and delayed recall.
The effects of a video game targeting inhibitory control in a social context will be tested in a Dutch sample of adolescent- and young adult smokers (between the ages of 16 and 26). It is expected that the adolescents and young adults who receive…
We hypothesize that aromatase-inhibitors will have lower efficacies in the presence of an abundant estrobolome and high ß-glucuronidase activity. It’s also unclear whether microbiota influences intestinal absorption of tamoxifen’s related metabolite…
We hypothesize that a certain shear load threshold exists, where an increase in the cytokine IL-1a is observed.
The hypothesis is that stratification of the referred population by the two referring screening radiologists using a validated design (BI-RADS, screening variant) can lead to a fast track workflow with only imaging tools, which would enable us to…