692 resultaten
We hypothesize that the CPA Talking-with-children-intervention will have a beneficial effect on the mental health and quality of life of maltreated children. We expect that children who participate in the CPA investigation (CPA Talking-with-…
We hypothesize that ingestion of potato protein increases muscle protein synthesis rates at rest as well as during recovery from exercise in young healthy males. We hypothesize that the muscle protein synthetic response to the ingestion of potato…
Patients with a BMI > 30 kg/m2 in the ICU have a higher incidence of pressure ulcers and wound infections in the ICU compared with patients with a BMI 18-25kg/m2. They develop them sooner during admittance and the severity and time to…
A two-week daily treatment with NAC (2400 mg/d) will change glutamate concentrations in the dACC and striatum in nicotine dependent subjects, while no effect of placebo on glutamate concentrations is expected. Treatment with NAC will show positive…
Simplified FLT PET parameter.
It is hypothesized that a flexible stepped care program for depression reduces the incidence of depression, severity of depression and anxiety symptoms and healthcare costs among primary care patients with diabetes type 2 and/or CHD and sub…
To determine whether a second dose of IVIg in GBS patients with a poor prognosis improves functional outcome after 4 weeks. Secondary outcomes include functional outcome after 8, 12 and 26 weeks, duration of mechanical ventilation, length of…
The main hypothesis is that use of Oncokompas will be superior to care as usual to reduce caregiver burden and to improve self-efficacy and quality of life, and it is expected that Oncokompas will improve quality-adjusted life years (QALYs) at…
Both intervention groups, ‘the stories we live by + counselor’ and ‘the stories we live by + peer contact’, are superior to the control group in terms of clinical outcomes (reduction of depressive symptoms and improvement of positive mental health).
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The hyperfiltration hypothesis implies that children with a solitary functioning kidney are at risk to develop hypertension, (micro)albuminuria and chronic kidney disease. We aim to develop an individualized risk profile for children with a solitary…
Currently the 3-year disease free survival of patients with locally advanced rectal cancer is about 50%. Current standard treatment for patients at high risk of failing locally and/or systemically includes pre-operative long course radiotherapy (5…
We hypothesize that increased disease activity (i.e. more inflammation) is associated with an increased risk of developing ID.
The gastric balloons are expected to remain in the stomach for approximately four weeks, after which they burst and are fecally excreted. It is further hypothesised that intragastric balloons can provide a surrogate stomach fill, inducing an…
The aim of the study is to examine how different working memory interventions address to the neurocognitive functioning and academic performance of children with AD(H)D.
In the proposed study we will investigate the effect
The objective is to investigate whether application of a stepwise work-up strategy in primary care patients with uncontrolled hypertension results in better blood pressure control in a cost-effective manner.
MBSR influences (1) emotional processing and (2) body awareness. The effect of MBSR on emotional processing is (3) mediated by body awareness.
The main objective is to examine the efficacy of a combined errorless learning and Goal Management Training (GMT) intervention for treatment of executive problems of patients with acquired brain injury (ABI) in the chronic phase (>6 months…
1) Online treatment for nightmares is more effective than a wait-list control group. 2) Efficacy of online treatment is mediated by 'nightmare mastery'