124 resultaten
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Addition of liposomal daunorubicin (DaunoXome®) to FLAG in the first reinduction course will result in improved treatment response with acceptable toxicity and without increased cardiotoxicity.
If the 'level of fitness dependant protocol' produces a higher VO2-max in comparison with the adapted Bruce protocol, then a relevant difference can be shown when the results are statistically analysed.
We hypothesised that this strategy could lead to a considerable and relevant change of prescribing behaviour in the desired direction.
The hypothesis to be tested is that the outcome in arm II (and Allo BMT) is better than in arm I.
Is diagnostic non-invasive coronary angiography with MS-CT a cost-effective alternative to diagnostic invasive coronary angiography in the management of patients with stable and unstable angina pectoris, referred for evaluation of the presence of…
The use of by filtration-leukocyte reduced blood transfusions in patients undergoing cardiac surgery, will result in lower alloimmunization frequencies compared to using buffy-coat depleted blood transfusions. This has previously been shown in…
The hypothesis to be tested is that the outcome in arm B is better than in arm A.
1. Can a larger percentage of Low SES women with depressive and/or stress related symptomatology be reached with an intervention when this contains an exercise component? 2. How effective is exercise only (B) compared to a control group (C) and does…
Infliximab counteracts the increased synthesis of tumor necrosis factor alpha (TNF-alpha), after which inflammation will decrease and recovery of the disease occur.
During chronic HIV-1 infection the immune system is chronically hyperactivated. This hyperactivation is considered as the main cause of CD4+ T-cell loss. Furthermore, HIV replicates most efficiently in activated CD4+ T-cells. In this study we try to…
10 Gy additional boost to the tumor bed will yield an increase in local control at 10 years from 88% to 93%, with still acceptable cosmesis.
We hypothesized that controlled ovarian hyperstimulation (COH) is of additional value to IUI in couples with a cervical factor and a poor prognosis, i.e. < 30% spontaneous pregnancy chance in the next year.
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The first hypothesis to be tested is that the outcome in arm B is better than in arm A. The second hypothesis to be tested is that the outcome in arm 2 is better than in arm 1.
We believe that a routine graft biopsy at 6 and 12 months together with graft function represents the best surrogate marker for late graft loss.
Does removal of allogeneic white blood cells by filtration reduce postoperative complications?
The effect of the TDM strategies on the viral load in terms of change from baseline (start or switch of therapy) to 96 weeks.
There is a need for assistance by primary care mental health workers in general practice in the Netherlands. General Practitioners (GPs) experience an overload of frequent attenders suffering from (co-morbid) psychological problems. For most GPs…