542 resultaten
We hypothesize that the CPA Talking-with-children-intervention will have a beneficial effect on the mental health and quality of life of maltreated children. We expect that children who participate in the CPA investigation (CPA Talking-with-…
Patients with a BMI > 30 kg/m2 in the ICU have a higher incidence of pressure ulcers and wound infections in the ICU compared with patients with a BMI 18-25kg/m2. They develop them sooner during admittance and the severity and time to…
Standard localized ligations are as feasible as doppler-guided ligations of hemorrhoid arteries.
1. 70% of patients will want risk information on the treatment options including prognosis; 2. Medical oncologists face difficulties while trying to judge which patients want the risk information?; 3. Effects of decision aid are positive.
A two-week daily treatment with NAC (2400 mg/d) will change glutamate concentrations in the dACC and striatum in nicotine dependent subjects, while no effect of placebo on glutamate concentrations is expected. Treatment with NAC will show positive…
PAS III-PC and PR-PAS III-PC are non-inferior compared to plasma PC in terms of recovery, estimated by the 1-hour CCI post transfusion
Simplified FLT PET parameter.
It is hypothesized that a flexible stepped care program for depression reduces the incidence of depression, severity of depression and anxiety symptoms and healthcare costs among primary care patients with diabetes type 2 and/or CHD and sub…
This trial hypothesizes that there are differences in morbidity and efficacy between both surgical techniques. It is also hypothesized that PerigeeTM is less morbid compared to anterior colporraphy as it is a minimal invasive technique. We can not…
To determine whether a second dose of IVIg in GBS patients with a poor prognosis improves functional outcome after 4 weeks. Secondary outcomes include functional outcome after 8, 12 and 26 weeks, duration of mechanical ventilation, length of…
Physiotherapy is effective in patients with mastectomy and axillary lymph node dissection (ALND), for shoulder/arm mobility and pain primarily and quality of life secondarily.
The age-specific seroprevalence of a cross-section of the Dutch population for the vaccinations used in the Dutch National Immunisation Programme.
Survival after screening for colorectal cancer with faecal occult blood test is increased compared with no screening.
Both intervention groups, ‘the stories we live by + counselor’ and ‘the stories we live by + peer contact’, are superior to the control group in terms of clinical outcomes (reduction of depressive symptoms and improvement of positive mental health).
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The hyperfiltration hypothesis implies that children with a solitary functioning kidney are at risk to develop hypertension, (micro)albuminuria and chronic kidney disease. We aim to develop an individualized risk profile for children with a solitary…
Currently the 3-year disease free survival of patients with locally advanced rectal cancer is about 50%. Current standard treatment for patients at high risk of failing locally and/or systemically includes pre-operative long course radiotherapy (5…
Imiquimod stimulates dendritic cell antigen presentation and migration to lymphnodes. Since dendritic cells are present in the dermis and epidermis, vaccination in the dermis could target these cells and, with simultaneous topical imiquimod…
The aim of the study is to examine how different working memory interventions address to the neurocognitive functioning and academic performance of children with AD(H)D.
We hypothesize that treatment of sickle cell patients with NAC results in reduced red cell PS exposure, reduced endothelial activation, increased NO availability, reduced coagulation activation and reduced inflammation detectable with specific…