97 resultaten
The goal of this study is to identify and validate recently discovered and novel biomarkers of pathophysiology, diagnosis, classification, disease activity, prognosis, treatment susceptibility, and treatment efficacy in chronic inflammatory…
The quality of human milk shows an association with the women's diet and lifestyle.
We hypothesize that diagnostic accuracy increases when, apart from cytologic samples, material is aspirated for thin layer preparation in endoscopic-ultrasound guided fine needle aspiration (EUS-FNA) of masses.
Alemtuzumab induction therapy in ABOi kidney transplantation lowers the incidence of cellular-mediated BPAR compared to rituximab induction, without affecting the number of antibody-mediated rejections.
Omniplasma results in a different concentration in coagulation factors after pediatric congenital cardiac surgery compared to fresh frozen plasma.
The aims of the present study are: 1. To give a comprehensive description of 200 adults (> 18 yr) with recently diagnosed adult-onset asthma (< 1 yr); 2. To define clinical, lung function or inflammatory or mixed phenotypes of adult…
In this study we will evalute the potention of HistoScanning guided biopsy to increase the detection rate of prostate cancer.
Stroke Risk Analysis (SRA) (Apoplex Medical, Pirmasens, Germany) is a Holter based algorithm that assesses the risk of underlying paroxysmal atrial fibrillation (pAF) from electrocardiographic anomalies in 1-24h snippets of Holter data while the…
Certain patient-specific factors contribute significantly to the outcome of delivery after a cesarean section in a Dutch hospital setting. These factors influence the decision to initiate trial of labour (TOL) or plan for an elective repeat…
The use of ECLS can lead to systemic inflammatory response. It is likely that ECLS affects red blood cell and platelet function after its initiation, the time course of these changes and their clinical relevance is yet unclear.
Characterization of subjects with non-atopic asthma and phenotyping of the disease by linking clinical, functional and molecular markers will: 1. Give more insight in the underlying pathophysiological mechanisms of non-atopic asthma; 2. Show that…
The aim of this programm is to stimulate people to follow the medical instructions and therefore to optimise the rehabilitation process and the bonehealing. In this project a prototypes was fabricated and will be used in twenty patients with a…
The implementation of antimicrobial coatings in health care results in an improved hygienic environment to support patient recovery and lowers the risk of a health care associated infection.
1. Flat adenomas are common findings in patients at average- or at high-risk for CRC; 2. Flat adenomas are characterized by a different molecular profile as compared to polypoid lesions; these molecular features are associated with an increased risk…
To determine the epidemiology, diagnosis and prognosis of enterovirus (EV) and parechovirus (HPeV) infection in Dutch children. Hypotheses: 1. EVs are one of the most important viral agents of infection in Dutch children; 2. EVs are the major cause…
Biomarkers like MR-proADM and CT-proAVP predict severity and outcome in critically ill COVID-19 patients. MR-proADM and CT-proAVP at admittance can be higher in non-survivors and biomarker clearance over the days will be higher in survivors.
We hypothesize that anxiety symptoms worsen after follow-up imaging compared to patients baseline anxiety levels.
Addition of alternative tests (TEG/ROTEM® and/or TGA) which reflect the whole hemostatic status of a patient might help recognizing the level of thrombin formation and fibrinolysis and improve care in ECMO patients and potentially reduce the risk of…
Specific areas of language production are affected in children and adolescents with classic galactosemia, in particular syntactic production. Further, it is hypothesized that the galactosmic patients will show a profile of general cognitive…
1. In Barrett Esophagus (BE), probe-based laser endomicroscopy (pCLE) provides better correlation with the histological diagnosis compared to detailed inspection with Narrow Band Imaging (NBI), reducing the high rate of false-positive findings with…