149 resultaten
Maintenance thalidomide delays the time to progression with 50% in patients who do not progress after > 3 cycles of pemetrexed containing chemotherapy.
To evaluate the anti-inflammatory effects of 3 months statin therapy on vessel wall inflammation by means of FDG PET/CT in patients with CKD.
Targeted Next Generation Sequencing (NGS) can distinguish benign pancreatic diseases, such as pancreatitis, from pancreatic malignancies during the diagnostic proces of patients with an uncertain diagnosis and treatment plan.
Is it possible / desirable to move Orencia treatment from the hospital to the home situation?
For patients with breast cancer who are not applicable for breast-saving treatment (because of tumor characteristics), who prefer an amputation or who undergo a prophylactic amputation an immediate breast reconstruction is a standard offer. A…
1. Regular physical follow-up can partly be replaced by nurse-led telephone follow-up, with at least similar quality of life (QoL), in breast cancer patients treated with curative intent. ( change in QoL < 5 points) 2. An informative/…
Multiple sclerosis (MS) is a brain disease, in which myelin sheaths in the brain and spinal cord are damaged. If repair of myelin damage is incomplete, nerve terminals will be irreversibly destroyed, leading to neurological symptoms. Ineffective…
Efficacy of occlusion therapy initiated in patients with untreated amblyopia between twelve and forty years of age is effective.
There is no formal statistical hypothesis to be tested in this Registry program.
Early diagnosis of cystic fibrosis (CF) and primary ciliary dyskinesia (PCD) combined with swift identification and treatment of pulmonary infections is important for the preservation of pulmonary function, quality of life and life expectancy. A…
relationship between CVR, CB, and vascular/inflammatory markers Co-localization of white matter damage and regions of low CVR Global and regional rsponse of CVR to simple trnasfusions, exchange transfusions and hydroxyurea.
We expect less sedentary time in the classroom and more standing time, from the objective data delivered by ActivPAL accelerometry. We expect beneficial findings on motivation, vitality, self-esteem, and mental well-being. We expect beneficial…
Aims: 1. To describe the prevalence and incidence of difficult-to-treat adult asthma in the Netherlands; 2. To describe factors associated with adherence with pulmonary medication in patients with difficult-to-treat airway disease; 3. To score the…
The current study evaluates whether accurate optical diagnosis of small colorectal polyps (<10mm) in vivo in a non-expert setting can be achieved, resulting in the omission of formal histopathology, which could make colonoscopy more efficient…
The primary goal is to show the capability of monocyte-derived DC after RNA electroporation for multiple antigens to induce an immune response. The secondary objective is to show clinical response.
When the optimal MRI protocol for imaging the sacral plexus and its branching nerves is known, the sacral plexus of children having neurogenic bladder dysfunction due to congenital spinal or sacral anomalies can be imaged. Because not much is known…
To prospectively assess the efficacy, feasibility and safety of a systemised endoscopic surveillance protocol in large multicentre HPS cohort.
Comparison of the clinical outcome of an HMPV infection in adult patients with a chronic respiratory disease compared to patients without a chronic respiratory disease: mortality, hospital stay
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