1169 resultaten
To demonstrate a 25% increase of docetaxel in tumor tissue after intravenous administration of CriPec® docetaxel compared to Taxotere®.
Hyperbaric Oxygen Therapy is an effective and feasible therapy option for therapy-refractory patients with perianal fistulas in Crohn's disease.
The purpose of the activity and heart rate monitor is to measure and track movement (acceleration) and heartbeat, and derive a number of health-related parameters, which can serve as basis for behavioral change programs leading to e.g. a healthier,…
We hypothesize that liraglutide treatment, initiated before cardiac surgery, is effective in lowering the number of patients needing perioperative insulin adjustments and reducing the total amount of insulin needed in the perioperative period when…
The objective is to assess whether myocardial microvascular perfusion and myocardial energy metabolism is impaired in HFpEF patients. Additionally we will evaluate whether endothelial dysfunction is associated with diminished myocardial perfusion (e…
We investigated the associations of maternal folic acid use and folate, vitamin B12 and homocysteine concentrations in early pregnancy with dental development in children. Secondly, we checked whether these associations were modified by MTHFR-C677T…
To investigate whether 3D VR ultrasound is of additional value in the detection of fetal anomalies in the first trimester when compared to the 2D ultrasound scan in the second trimester of pregnancy (=usual care) within a high risk population.…
The primary objective is to investigate whether the rebreathing apparatus or the steady-state apparatus should be used as a diagnostic tool in the MST. The primary objective is answer by means of sub questions, which involve; the repeatability of…
A higher (animal) protein and a higher essential amino acid intake (especially leucine) are associated with less decline in mid-thigh muscle cross-sectional area over a 5-year period.
The majority of patients admitted outside a dedicated Burn Center will have a maximum of 10% Total Body Surface Area burned.
The aim of the study is to investigate whether a verbal suggestion concerning the relaxation exercises alone or in combination with actually performing relaxation exercises can alter self-reported stress and psychophysiological measurements of…
The use of an interactive app during the perioperative period, when undergoing colorectal surgery, will activate and stimulate patients and therefore result in higher compliance to the ERAS-protocol.
It is hypothesized that strenuous exercise at high altitude causes increased thrombin generation, but that this effect will be attenuated during prolonged exposure and repeated exercise.
Dried Blood Spot is a reliable method to determine antipsychotic blood levels.
The use of incisional management system reduces the incidence of wound dehiscence in low and high-risk patients undergoing plastic surgery.
"Het primaire doel van het onderzoek is het evalueren van de fixatie en migratie patronen van de Persona Partial Knee (Zimmer Biomet, Warsaw, IN) in vivo, met model-based RSA. Het secundaire doel van het onderzoek is het analyseren van de korte…
Repetitive ePIPAC-OX as a palliative monotherapy is a feasible, safe, tolerable, and potentially effective treatment for isolated unresectable colorectal peritioneal metastases, with low and predictable costs and a low systemic uptake of oxaliplatin…