4296 resultaten
The aim of this study is to describe the last phase of life of people with young-onset dementia. The research questions for this prospective observational study are: 1. What is the practice of end of life care in people with young-onset dementia…
1. The predictive biomarkers for tumor response to immuno modulating therapy will be a combination of adaptive and innate immune status per patient that will be estimated with a tumor biopsy before, 6 weeks after start treatment (optional) and at…
The primary objective of the present study is to investigate the effectiveness of the Resource Groups (RG) on patient outcomes compared to care as usual alone for people with severe mental illnesses. It is hypothesized that participation in the RG…
We hypothesize that the quality of diabetes treatment, measured as glycaemic control, is worse in patients with T2DM and colorectal- and breast cancer treated with curative intent, compared to T2DM patients without cancer, at 1 and 2 years after…
Preoperative planning with x-ray-based PSI have comparable outcome as 3D used MRI-based PSI resulting in indirectly reduced costs on storage of implants and instruments.
Extension of SAD PK/PD Model, confirmation of SAD PD effects
Patients with Type 2 diabetes have been shown to have an increased risk for developing cancer, especially obesity related cancers. There is some evidence that within the class of sulfonylureas there is a difference in cancer risk; gliclazide could…
A Community One Health approach (bringing human and animal health together at the community level) improves disease surveillance efforts by Community Health Workers, health knowledge and behavior and physical health in study populations.
The Victoria modules are thought to have a positive effect on acknowlegdement for adversities and risk awareness. This can be used to take acceptable risks in rehabilitation process. This will then lead to more societal participation and less…
Feasibility and reliability of prehospital triage in patients with thoracic complaints/pain appropriate to a suspicious ACS
This study will evaluate the effectiveness of IPAS, with and without additional support, to improve objectively measured PA levels. We expect that IPAS will raise the level of PA more than normal care (UC) with a higher expected effect for IPAS +…
The primary objective of this study is to statistically determine the optimal contact-pressure (compression force divided by breast-paddle contact area) for breast compression in Digital Breast Tomosynthesis. In this study, ¡°optimal¡± is defined as…
The WALK gait retraining program is more effective to treat patients with symptomatic mild to moderate knee OA and an extension deficit, compared to a standardised treatment protocol based on the KNGF (royal Dutch association of physiotherapists)…
The main objective is to investigate whether actigraphy can be used as an objective measure to designate the presence or severity of apathy in patients with schizophrenia. To this end, we will measure activity levels using an accelerometer (i.e.…
The overall hypothesis is that the developed exercise therapy program is feasible, safe and improves cardiorespiratory fitness, functional performance, reduces CV risk factors and disease activity in patients with RA and high CV risk.
The aim of this study is to evaluate whether consulting a sexologist will have better outcomes considering quality of life and sexual function in women who underwent surgical treatment for (pre)malignant vulvar lesions.