244 resultaten
Therapeutic drug monitoring is effective in optimizing treatment with tobramycin and reduces side effects.
The hypothesis to be tested is that arm B is tolerable and that the outcome in arm B is better than in arm A.
Chronic cold exposure will increase: 1. Basal metabolism and facultative thermogenesis; 2. Brown adipose tissue activity and volume; 3. Skeletal muscle mitochondrial uncoupling and result in BRITE cell recruitment.
Good Inter-observer agreement for important markers such as bowel wall thickness and Doppler activity
We hypothesize that rectal NSAID prophylaxis use will have significantly risen in comparison to the 2013 survey. We hypothesize biliary endoscopists will show a significantly better risk factor recognition than general gastroenterologists. We…
We hypothesize that group medical appointments will enhance adherence to treatment and self-efficacy in patients with sickle cell disease, as well as increase quality of life, and satisfaction with the treating physician and nurse. When performing…
The overall objective of this study is to assess safety of AG-348 and provide proof of concept of the efficacy of the drug in SCD patients. Based on currently available data, we hypothesize that the benefits of treatment of sickle cell disease…
Delivery of a generic MBSR training to patients who visit a memory clinic with cognitive complaints, and who show no clinical signs of a cognitive disorder, is feasible.
It is hypothesized that a low protamine-to-heparin ratio leads to improved hemostasis after cardiac surgery with cardiopulmonary bypass as compared to a high ratio as measured by rotational thromboelastometry, and reduces postoperative blood loss…
The annual incidence of castration-resistant prostate cander (CRPC) in the Netherlands is estimated at 2868 patients. After development of CRPC, survival with best supportive care is not expected to exceed 12 months. Fortunately, several new…
This study primarily aims to explore changes in physical activity pattern and energy expenditure in head and neck cancer patients, during and after treatment with surgery with or without (chemo)radiation. The following primary null hypotheses will…
Oral exposure time and energy content of the gastric load both affect subjective feelings of satiety and gastric emptying rate. It is expected that a longer oral exposure time and a higher gastric energy content would both increase subjective…
There are no effective interventions to prevent dehydration of elderly people available. Therefeore the RPHS West-Brabant, together with the Gneral Practice de Keen, decided to develop and analyse the efffect of an education strategy. Besides that…
- A new sensorbased gait analysis measurement as a simple and quick diagnostic/monitoring tool to evaluate joint status and changes in gait pattern in hemophilia patients. - Possibility to detect a disturbed gait pattern in clinically asymptomatic…
Implant survival rate of 90% or higher
Parents who receive the two-day EMDR treatment will report significantly lower trauma scores and psychological comorbidity scores post-treatment compared to the wait-list group.
The aim of the current study is to test whether online training of a positive attentional bias or positive interpretation bias is successful in increasing resilience, reducing internalizing symptoms and preventing clinical disorders (anxiety/…
We hypothesize that daily oral administration of increasing dosages of Eubacterium hallii, an anaerobic intestinal bacterial strain, can exert beneficial effects on insulin sensitivity and liver fat.
Two hours of end-ischemic hypothermic oxygenated perfusion via both the hepatic artery and the portal vein is feasible and safe in resuscitating liver grafts procured from donation after circulatory death donors.
Consumption of the new developed GUM will decrease the incidence of upper respiratory tract infections (URTI) and/or decrease the duration of acute gastrointestinal tract infections (GITI) in Asian toddlers