This study primarily aims to explore changes in physical activity pattern and energy expenditure in head and neck cancer patients, during and after treatment with surgery with or without (chemo)radiation. The following primary null hypotheses…
ID
Bron
Verkorte titel
Aandoening
physical activity, energy expediture, Head and neck cancer, malnutrition / lichamelijke activiteit, energiebalans, hoofdhalskanker, ondervoeding
Ondersteuning
Hanze university of applied science, Groningen, the Netherlands
Hanze university of applied science, Groningen, the Netherlands
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Daily step count (steps/day)<br>
Measured energy expenditure (in kcal and METs)
Doel van het onderzoek
This study primarily aims to explore changes in physical activity pattern and energy expenditure in head and neck cancer patients, during and after treatment with surgery with or without (chemo)radiation.
The following primary null hypotheses will be tested in this study:
Physical activity of head and neck cancer patients treated with surgery, with or without postoperative (chemo)radiation, does not decrease during treatment period.
Total and resting energy expenditure of head and neck cancer patients treated with surgery, with or without postoperative (chemo)radiation, does not change during treatment period.
Measured energy expenditure does not differ from estimated energy expenditure in head and neck cancer patients treated with surgery, with or without postoperative (chemo)radiation.
The secondary aim of this study is to gain insight in perceived exercise barriers and facilitators, and exercise preferences of head and neck cancer patients.
Onderzoeksopzet
Head and neck cancer patients will be assessed three times: 1) one week before start of treatment, 2) six weeks after end of treatment, and 3) four months after end of treatment.
Onderzoeksproduct en/of interventie
Not applicable: observational study
Measurements:
Physical measurements during the study:
Body weight
Length
Muscle mass/fat-free mass: mid upper arm muscle circumference (by means of mid upper arm circumference and triceps skinfold), thigh and calf circumference, bio-electrical impedance analysis
Muscle strength: hand grip strength (Jamar hand grip dynamometer), chair to stand test
Resting energy expenditure: indirect calorimetry (Cosmed K4b2)
Questionnaires:
Malnutrition: Patient-Generated Subjective Global Assessment (PG-SGA)
Frailty: Frailty Instrument for Primary Care of the Survey of Health, Ageing and Retirement in Europe (SHARE-FI)
Fatigue: MVI20
Self efficacy: Exercise Self Efficacy Scale
Self regulation: Self regulation Questionnaire Exercise
Motivation: Stage of Change Exercise
Performance status: WHO performance status scale
Tumor- and treatment-related symptoms: EORTC QLQ-HN35
Publiek
Eyssoniusplein 18
M. Sealy
Groningen 9714 CE
The Netherlands
050-5953604
m.j.sealy@pl.hanze.nl
Wetenschappelijk
Eyssoniusplein 18
M. Sealy
Groningen 9714 CE
The Netherlands
050-5953604
m.j.sealy@pl.hanze.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
- Newly diagnosed T1, T2, T3 or T4 malignancy in the oral cavity, larynx, oro- or hypopharynx, to be treated with surgery with or without (chemo)radiation
- Age: at least 18 years
- Able to understand and speak the Dutch language
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
- Second primary tumor, outside the head and neck region
- Wheel chair dependency
- Comorbidity with a contra-indication for physical exercise
- Severe cognitive disabilities
- Skin allergy or highly sensitive skin
- Palliative treatment
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
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Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL4676 |
| NTR-old | NTR4828 |
| Ander register | METC UMCG : METC 2012/063 |