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Antidepressant medication does not add any effect to usual consultations by general practitioners in patients with minor and mild-major depression.
Closing wedge osteotomy with plate fixation only will result in earlier mobilisation and better one year results considering pain and function then staple and cast fixation.
We hypothesize that in preterm infants with a gestational age below 34 weeks a low threshold intervention (progressive PHVD with a ventricular enlargement above the 97th centile for gestational age according to Levene and a diagonal width…
A self-management programme guided by doctors and a specialist asthma nurse through information and communication technology will improve asthma related quality of life in a cost-effective way.
Accelerometers are already widely used in research in chronic diseases, but also increasingly used by health professionals in general practice. It is however not known in occupational therapy, if these measurements are feasible. Furthermore, no…
Efficacy of minimal intervention strategy (isolated training of the lumbar extensors) with the use of a control group receiving usual care.
Efficacy of inhaled DNase in children with an airway malacia and a lowerrespiratory tract infection.
We hypothesize that DNase improves mucociliary clearance and mucus retention in patients with (trachea)bronchomalacia during a lower respiratory tract infection, resulting in a faster resolution of symptoms and shorter duration of a lower…
We expect to find differences in taste related brain regions, i.e. the primary and secondary taste cortex (AIFO and OFC) and brain regions involved in reward and energy processing, such as the striatum, amygdala and cingulate cortex.
To explore the short term safety and tolerability of 2-IB and the pharmacokinetic profile of 2-IB when given on top of therapeutic hypothermia
On the assumption that N-acetylcysteine might prevent acute contrast induced nephropathy in critically ill patients, we study the effects of prophylactic intravenous administration of N-acetylcysteine in critically ill patients with renal…
A sustained inflation with a mechanical device and early nasal continuous positive airway pressure is a more effective management strategy for RDS in preterm infants than conventional intervention with a self-inflating mask and bag and reduces the…
To assess whether the genetic architecture of this severe therapy-resistant SCZ phenotype differs from the broad DSM-based SCZ phenotype.
We will test the hypothesis that ongoing use of risperidone is superior to placebo with regard to behavioral symptoms in children and adolescents who have used risperidone for a year or longer.
not applicable
The overall survival in the arm treated without chemotherapy (TNM-stage II or III tumours) is expected to be approximately 60%. Assuming an improvement in overall survival from 60% to 70% in the arm treated with chemotherapy (TNM-stage II or III…
Surgery is the standard therapy for esophageal cancer. However, 30% of the resections are irradical. It is thought that preceding chemoradiotherapy will improve the surgery results.
Multidisciplinary, goal-attained and individualized rehabilitation after knee arthroplasty will result in more satisfaction regarding activities (level of activities and overall satisfaction) in younger knee arthroplasty patients (<65 years).
Research questions: 1. Is a multidisciplinary intervention programme more effective than usual care in preventing new falls and functional decline among community-dwelling elderly people who visit a GP cooperative and/or A&E department at a…
Early surgical treatment (exploration followed by resection (pancreatoduodenectomy or bypass) in patients with obstructive jaundice due to a pancreatic head tumor is equivalent in terms of severe complications of treatment compared with patients who…