2168 resultaten
To determine the influence of optical quality on perimetry for phakic and pseudophakic healthy and glaucoma patients. To determine the influence of CLE on perimetry and optical quality for PAC patients.
Our null hypothesis is that there are no differences in tibiofemoral joint kinematics after ACL reconstruction with LET and the tibiofemoral joint kinematics after ACL reconstruction without LET. Our alternative hypothesis is that ACL reconstruction…
We hypothesize that 1) fasting duration may affect the central serotonin and dopamine systems, either centrally or indirectly through effects on peripheral input to the central nervous system, and 2) the effect of fasting may be changed in obesity.
The aims of the study are: To investigate the short-term effectiveness of antecedent and consequent behavioral parent training techniques for parents of children (four to twelve years old) with attention-deficit/hyperactivity disorder (ADHD) on…
Survivors of sepsis are at high risk for the development of chronic kidney disease (CKD), cardiovascular events and mortality. Mitochondrial dysfunction, which mainly results from increased generation of free radicals, plays a key role in the…
The aim of this study is to show whether TDM leads to a lower proportion of patients with drug levels below the predefined TDM targets after 12 weeks
With implementation of the AWR and APWR by the ED triage nurse we expect a reduction in the total number of radiographs requested, without missing any clinical relevant fractures. We also expect a reduction in overall waiting times at the ED and…
We hypothesize that the epigenetic changes that are related to childhood trauma provide a treatment target for succesful treatment with SAMe of persistent depression in bipolar disorder
Victims of IPV, living in an unsafe and unhealthy situation, are faced with a broad range of physical and emotional symptoms. Standard and easy-accessible care to facilitate change into a safer situation is lacking. The project aims to launch an…
Infant formulae with higher levels of milk fat result in improved fatty acids absorption as compared to standard formula.
The plasma concentrations of inflammatory mediators of AP subjects are similar to those of non-AP controls and elimination of the endodontic infection does not result in changes of the systemic inflammation. Finally ) to investigate the microbiome…
Training for the HandbikeBattle and handbike training in general, will have a positive effect on physical health, physical fitness and quality of life in wheelchair dependent individuals.
Vibrotactile feedback from a 'smart' fork reduces the eating rate of a teenage girl suffering from brain damage that causes her not to detect hunger or satiation
We hypothesize that in healthy individuals with Early-life stress (ELS), THC, which directly targets the endocannabinoid system, is more effective than hydrocortisone in improving stress adaptation and extinction learning in an experimental model of…
Some smokers manage to quit completely by exclusively switching to e-cigs. However, some e-cig users tend to keep smoking their regular tobacco cigarettes (possibly less than before) in combination with their e-cig. The term “dual use” refers to…
We hypothesize that Network Pain Rehabilitation Limburg will be feasible in daily practice based on the found barriers and facillitators and perceived quality of care. Moreover, the effect of the different treatments on the physical functioning of…
Primary Objective: To gain insight in the disease mechanisms of IBD. Secondary Objective(s): To identify biomarkers and study functional and mechanistic properties of the mucosal immune system, gut and oral microbiome, epithelium, mucus barrier,…
This study aims to assess: - the efficacy of 9 cycles of ixazomib, daratumumab and low dose dexamethasone in newly diagnosed unfit and frail multiple myeloma patients. - the value of geriatric assessments to predict both feasibility and efficacy…