1923 resultaten
The use of structural biomarkers (e.g. fundus autofluorescence imaging, optical coherence tomography or a combination thereof) may show a much more gradual progression that is indicative of functional vision loss at a later stage.
This is a clinical trial in the home environment of 60 epilepsy patients to investigate the sensitivity and positive predictive value of a multimodal sensor system (‘LivAssured’) for the detection of nocturnal motor seizures.
To identify candidate antigens for the development of a prophylactic Staphylococcus aureus vaccine by studying expression profiles of host and pathogen determinants during natural infection.
The use of platelets in addition to mucosa advancement flap in the treatment of complex peri-anal fistula will reduce the recurrence rate of these fistulas.
The effects of a video game targeting inhibitory control in a social context will be tested in a Dutch sample of adolescent- and young adult smokers (between the ages of 16 and 26). It is expected that the adolescents and young adults who receive…
It is hypothesized that the Silbernagel exercise program yields at least similar results in terms of symptom reduction (VISA-A score and VAS score)compared with the Alfredson eccentric exercise program.
What is the relation between disease activity, treatment, and metabolic syndrome / insulin resistance.
Botulin toxin driven treatment ylieds the highest efficacy when injected into the external anal sphincter.
Physicians will speak of an 'asthma cough' and while coughing is one of the symptoms of asthma, the specificity of coughing as a predictor for asthma is known to be low. It is hypothesized that the coughs and it's derived parameters,…
There is a correlation between the threshold to elicit a MEP by stimulating the DBS lead and the distance between the DBS lead and the internal capsule
The intradermal vaccination of a fractional dose of mRNA-1273 LPN vaccine (Moderna) is safe and non-inferior in eliciting neutralizing antibodies against SARS-CoV-2 to the standard dose injected intramuscularly
Vitamin D supplementation reduces the incidence of delayed union in fracture patients with a vitamin D insufficiency, compared to placebo.
There is growing evidence that gut permeability (or a 'leaky gut') can be linked to metabolic health and might therefore be involved in development of metabolic disorders related to the metabolic syndrome. We hypothesize that gut…
We hypothesize that ESD will be associated with longer procedure times but lower costs. For lesions that prove to be benign, we hypothesize that ESD will lead to a higher number of R0 resections and lower recurrence rates, particularly for lesions…
We expect changes in each of the three tasks, with less words remembered (15 word test), a larger Simon effect (Simon task) and slower performance (TMT) in the repeated assessment compared to the first assessment. We also expect changes in each of…
Magnetic Resonance Direct Thrombus Imaging (MRDTI) can be an accurate test for diagnosing Upper Extremity Deep Vein thrombosis (UEDVT)
In this RCT we investigate the effects of two school-based physical activity interventions (aerobic exercises versus coordinative exercises) in primary school children on executive functions and academic achievement. We hypothesize that both aerobic…
Recurrent miscarriages is defined as three or more consecutive miscarriages prior to the 20th week of gestation. Whenever the diagnosis ‘recurrent miscarriages’ is established, an underlying cause may be identified in about 25-50% of cases. A…