1611 resultaten
We hypothesize that induction of labour in patients with gestational hypertension, deteriorating chronic hypertension or preeclampsia between 34 and 37 weeks reduce the maternal morbidity but might increase the RDS rate in neonates, compared to…
We hypothesize that the CPA Talking-with-children-intervention will have a beneficial effect on the mental health and quality of life of maltreated children. We expect that children who participate in the CPA investigation (CPA Talking-with-…
We hypothesize that it is possible to culture circulating tumor cells obtained by leukapheresis into organoids.
Synflorix (PCV10) and Prevenar-13 (PCV13) are comparable in inducing cellular and humoral immune responses in Dutch infants for the 10 overlapping serotypes in the vaccines. Differences are expected for three serotypes that are present in Prevenar-…
The aim of this study is to pass of the care for patients with fibromyalgia more efficiently through the cooperation of the rheumatologist and the nurse specialist. Because of this, the rheumatology outpatient department can be relieved partly,…
It is expected that the urinary and serum level of intestinal fatty acid binding protein (I-FABP) and the urinary level of Claudin-3 have prognostic relevance for early identification of patients at risk for intestinal ischemia-related morbidity or…
Cap-assisted colonoscopy may improve the adenoma detection rate in CRC screening participants.
A nutrient dense infant formula promotes growth more effectively than current practice.
We hypothesize that ingestion of potato protein increases muscle protein synthesis rates at rest as well as during recovery from exercise in young healthy males. We hypothesize that the muscle protein synthetic response to the ingestion of potato…
Evidence based medicine is the standard for current clinical practice. Guidelines and decision rules are developed to support medical decision making. Application of decision rules are supposed to improve efficiency and quality of care by early…
Patients with a BMI > 30 kg/m2 in the ICU have a higher incidence of pressure ulcers and wound infections in the ICU compared with patients with a BMI 18-25kg/m2. They develop them sooner during admittance and the severity and time to…
The study aims to assess the efficacy (in terms of growth response over the years of treatment, including final height) and safety of a treatment regimen consisting of: 1. Authentic biosynthetic growth hormone (GH) in a dosage of 4 IU/m2/day between…
Electrical stimulation on the foot and lower leg will increase the blood flow and thereby the amount of oxygen to the skin. Our overall hypothesis is that this will help to reduce the risk of decubitus on the heel. The specific hypothesis for this…
Disturbances in the circadian rhythm could be a possible cause for development of delirium.
In patients presenting with a non-ST elevation acute coronary syndrome with (new) ST segment depression and/or positive troponin-T, who undergo PCI, treatment with a dexamethason coated stent will reduce the incidence of restenosis at 6 month follow…
treatment with STB wound dressing in combination with nasal saline irrigation, after coblation of the inferior turbinates, provides better wound healing compared to nasal saline irrigations only.
Simplified FLT PET parameter.
There are two research questions: 1. Does cognitive behavioural therapy (CBT) in groups lead to a significant decrease of fatigue and functional impairment of CFS patients compared to a waiting list condition? 2. For which patient is group therapy a…
Fluorescent near-infrared imaging can accurately detect pancreatic cancer non-invasively during a whipple procedure.
Physiotherapy is effective in patients with mastectomy and axillary lymph node dissection (ALND), for shoulder/arm mobility and pain primarily and quality of life secondarily.