3147 resultaten
The following hypotheses will be examined: a. patients with multiple sclerosis who become cognitively impaired may experience an increase in pain experience (due to white matter lesions) b. hyperesthesia is known to be predictive of central…
First, it will be investigated which is the best diagnostic tool for imbalance in CP. Second, it will be determined whether balance training can promote balance control in CP, and whether the improvements will be maintained after a follow-up period…
This study aims to implement and evaluate an advance care planning (ACP) intervention for elderly nursing home patients with a limited life expectancy. The intervention consists of ACP discussions integrated with a structured multidisciplinary…
Prevalence of PNH in selection of patients with DVT. Patients younger than 30 years of age. patients with DVT on unusual places.
Based on the results obtained in our previous study (Ruiter, Kolk, Rietveld, Dijkstra & Lotgering, 2011), we hypothesise that: - The experimental changes to the scenarios and new quantitative scoring procedure of the Amsterdam-Nijmegen…
We hypotheze that direct removal of the urine catheter after an LH (total laparoscopic hysterectomy and laparoscopic supracervical hysterectomy) is associated with similar (or better) outcomes compared to delayed catheter removal after surgery,…
We hypothesize that there is no difference in clinical and radiological outcome when using PSG for UKA compared with results from the literature describing results from conventional UKA surgical techniques.
Exploration of the effects of AAT in adults with an Autism Spectrum Disorder (because this study has an explorative character, there is no hypothesis formulated)
The aim of this study is to develop and evaluate a health behavior change and social network enhancement intervention for low-income households in Apeldoorn who receive care for multiple problems (such as financial debts, domestic violence,…
screening for cardiovascular diseases will reduce coronary heart disease-related mortality and morbidity
Does MS grey matter pathology progress faster in regions with more damage in connected white matter?
Our hypothesis is that MS grey matter pathology, and thereby disease burden and clinical outcome, can be better predicted by looking at damage in the connected white matter in early RRMS patients
Treatment of a subcapital metacarpal fifth fracture with a compression bandage gives the same functional outcome a treatment with paris plaster
To develop a dosing nomogram of irinotecan in patients homozygous polymorphic for UGT1A1*28 and/or UGT1A1*93 in order to reduce the incidence of severe irinotecan-associated toxicity, defined as febrile neutropenia in the first 2 cycles (amendment…
A combination therapy (MDT and TESIs) is effective and cost-effective compared to usual care among herniated nucleus pulpos patients with an indication for a lumbar herniated disc surgery
Trends in and variability of vital signs reveal hidden information about the state and deterioration of the patient compared to absolute values of vital signs.
This study will be an open observational study with the objective to test the feasibility of the mDLS. The variability of the methodology over time will be assessed. Blood flow and coagulation status assessed by mDLS and LSCI will be compared with…
Acid-reducing drugs, such as PPIs, may profoundly decrease solubility and, as a result, (negatively) affect the bioavailability of afatinib. Since a PPI is often used concomitantly during afatinib therapy, this DDI confronts physicians, patients,…
Rationale: There is no cure for dementia. Physical activity could be an alternative to medications in an effort to slow cognitive decline In healthy elderly subjects physical activity leads to improved cognition. Objective: Part 1: Main objective:…
To evaluate the anti-inflammatory effects of 3 months statin therapy on vessel wall inflammation by means of FDG PET/CT in patients with CKD.