61 resultaten
The COL3A1 polymorphism is a inheritable genetic defect, responsible for the increased susceptibility to pelvic organ prolapse in women.
PD-L1 is up to now the only marker that has been validated for the selection of patients treated for non-small cell lung cancer who might benefit from the treatment with PD-1/PD-L1 inhibitors. Thus far, PD-L1 status is assessed with histology, being…
Patients undergoing breast conserving surgery in combination with oncoplastic surgery are more satisfied with the cosmetic result and have a higher quality of life
Non invasive hemodynamic monitoring is as good as invasive monitoring
We hypothesize that the underlying mechanisms of the varying response in multiple parameters within an individual can be attributed to variability in the causal path between drug administration, drug tissue distribution, and tissue receptor…
Fatigue affects central nervous system function and, in the setting of the medical profession, could influence specialist performance, patient care and safety. ln contrast to other industries, for example the aviation industry, there are no "…
About 10-15% of the population suffers from chronic insomnia. Structurally poor sleep can have unpleasant consequences for people's health and quality of life. Therefore, proper treatments are of great importance. Fortunately, Cognitive…
18F-FDHT PET/CT is expected to be a predictor of response in patients with metastasized castration-resistant prostate cancer to be treated with enzalutamide
The main hypothesis is that compared to TAU, BA will be more effective and less costly. A secondary goal is to explore several potential mechanisms of change, as well as predictors and moderators of treatment outcome of BA for late-life depression.
The primary objective of this study is to review the prevalence of pelvic organ prolapse after laparoscopic hysterectomy compared to vaginal hysterectomy. Because the uterosacral ligaments are the important structure for vault suspension after…
Magnetic Resonance Direct Thrombus Imaging (MRDTI) can be an accurate test for diagnosing Upper Extremity Deep Vein thrombosis (UEDVT)
There is growing evidence that gut permeability (or a 'leaky gut') can be linked to metabolic health and might therefore be involved in development of metabolic disorders related to the metabolic syndrome. We hypothesize that gut…
Several reasons for clozapine discontinuation are known, but the current evidence identifying patients who are at risk of discontinuation of clozapine is small and not always consistent. Also cultural differences may question if international…
We hypothesize that socioeconomic inequalities in diet quality are partly explained by differential dietary costs.
The aim of this study is to develop and validate an age-specific checklist that can help clinicians to identify elderly patients with personality disorders in need of highly specialized mental health care.
A dual mobility cup with a small size head (22 mm) is more likely to result in intraprosthetic dislocation than a bigger size head (28 mm).
Intraoperative verification of paranasal sinus malignancy resection with cone-beam computed tomography will lead to a higher rate of radical resection
We hypothesise that the relations of total fat and fatty acid (FA) subtypes (SFA, MUFA, or PUFA) with CHD are modified by their food source. We aim to directly compare relations of FA subtype intake from dairy and meat with risk of CHD by using…
Vitamin D plays an integral role in calcium and phosphorus homeostasis. A low vitamin D status can occur as a result of reduced synthesis due to lack of sun exposure, decreased intake or absorption, increased hepatic catabolism, or decreased…