936 resultaten
In this RCT we investigate the effects of two school-based physical activity interventions (aerobic exercises versus coordinative exercises) in primary school children on executive functions and academic achievement. We hypothesize that both aerobic…
The primary hypothesis for this data collection study is that there are various surrogate physiological parameters for inferring blood pressure (BP), which can be more easily obtained than the direct BP measurement. An example of such surrogate…
To assess in a randomized comparison the effect of Ibrutinib added to 10-day decitabine treatment on the cumulative CR/CRi rate after 3 cycles. To assess the safety and tolerability of Ibrutinib added to 10-day decitabine treatment for AML (…
Prevention of the progression of TMD to ML-DS by chemotherapeutical profylaxis can be possible.
The use of videoglasses will lead to more anxiety reduction than hearing preferred audio in patients undergoing surgical procedures under local anesthesia.
Chronic heart failure (CHF) is a clinical syndrome resulting from a decreased cardiac output, insufficient to maintain adequate tissue oxygenation. Eventually, inadequate tissue oxygenation will lead to pathological alterations, especially at the…
What are the motivations of women in the Netherlands to choose UC and what are their beliefs on childbirth in general and in relation to current Dutch maternity care? This study primarily aims at understanding women’s motivations in declining (parts…
Teres Major muscle transfer group will show significant better improvement in active abduction and external rotation than the LD group after 1 year.
Intravesical instillation of BCG is a widely accepted strategy to prevent recurrence of non muscle invasive bladder cancer. The most accepted treatment schedule is induction of BCG: weeks 1 through 6 plus maintenance (weeks 1,2,3) at months 3,6 and…
DBS-related cognitive decline and psychiatric side-effects in Parkinson's disease (PD) patients can be studied from a functional- and structural network point of view. We will characterize functional and structural brain networks in PD patients…
This study aims to underpin the delivery of longstanding exercise therapy in the subgroup of patients with RA and complex disability. There are 3 research questions to be addressed: 1. Is longstanding, optimized active exercise therapy more…
Does sildenafil improve tumour perfusion?
A mathematically correct PK-PD model will be developed that describes the depressant effect of propofol on breathing with and without a background of remifentanil.
We hypothesize that selfmanagement support via an internet based service in addition to usual care will improve health related quality of life in patients with severe asthma who have participated pulmonary rehabilitation in specialized asthma…
•To assess the safety and tolerability of induction doses of ABP-700 and determine dosing regimens that reliably produce drug induced unconsciousness and the pharmacodynamic conditions necessary for induction of general anesthesia with ABP-700 alone…
The main objective of this study is to compare upper extremity dysfunction (UED) following slender TRPCI using small bore catheters (5F) compared to standard PCI using regular size guiding catheters (6F) and conventional stent techniques at two…
Psychological risk factors will cluster in multiconstruct patient profiles predicting outcome. A network of biological and behavioral mechanisms explain the relationship between these psychological risk clusters and outcome after PCI. The ESC…
We hypothesize that BCG vaccination may reduce hospital admission and improve the clinical course of symptoms of elderly people during the SARS-CoV-2 outbreak.
DOACs are non-inferior to LMWH with regard to the risk of ICH in patients with brain cancer requiring anticoagulation.