121 resultaten
the present study investigates whether a small-scale stay in an enriched green environment in a care center is related to a slower progression of cognitive functions, better mood, less behavioral problems, and a higher quality than if standard care…
The adherence of NOACs in atrial fibrillation in specific subgroups is low. Identifying these non-adherent patients in daily clinical practice is important to minimise stroke and bleeding risk. We hypothesize that NOACs are relatively often…
HYPOTHESES: We hypothesize that the PAMA condition in comparison to the Usual Care condition will: 2. Lead to more high risk smokers engaging to quit 3. Lead to more informed decision to quit smoking by smoking patients 4. Lead to more evidence…
1. An early screening at 1y of corrected age will identify preterm children with an increased risk of developing visual processing dysfunctions 2. Early visual rehabilitation from 1y of corrected age will benefit the visual and neurocognitive…
By means of image-guided surgery, we can navigate the procedure by visualization of pre-operative planned MR and/or CT based 3D models and providing the surgeon with real-time feedback on the position of the surgical tool within this model and more…
LRRK2 activity is linked to central mechanisms of Parkinson’s disease pathology through its role in lysosomal function, and LRRK2 kinase inhibitors, such as DNL201 (IND Number: 133665) represent a new class of therapeutics with potential to address…
Obesity is significantly associated with Atrial Fibrillation (AF), and, interestingly, if obese patients loose weight, AF dissapears in 50% of the cohort. On the other hand, adipose tissue (AT) functioning alters up weightchange. Therefore we…
Ex vivo organoid response correlates to in vivo response to standard first line treatment in mCRC patients on a metastasis level, therefore organoids can be used to predict response to therapy and select patients for a specific treatment.
We hypothesize that the Armed4stroke program will: 1) Increase patients self-reported level of mobility, measured with the Stroke Impact Scale. 2) Smoothen the transition to patients own home situation, which will shorten the length of stay for…
Several studies have looked into hyperkalemia as adverse drug reaction of co-trimoxazole. Many of these previous studies have shown that co-trimoxazole induced hyperkalemia is a potentially dangerous adverse drug reaction, especially in high-risk…
Compared to placebo treatment with low dose amitriptyline or mirtazapine during 16 weeks will improve subjective insomnia in insomnia disorder patients in general practice.
Contralateral exploration during unilateral inguinal hernia repair in children younger than six months reduces the incidence of contralateral inguinal hernia and decreases the number and total duration of operations, anesthesia time and hospital…
Hypothetically, the elimination half-life of midazolam in elderly intensive care patients is double prolonged.
We hypothesize that 18F-FDG is a valide marker for metabolic activity in adipose tissue and even more pronounced in type 2 diabetes.
First, we hypothesize that IHNR will shorten the time to regain (baseline) HRQoL. Second, we hypothesize that the program will enhance the ability to resume work-related and daily activities, and will lead to a reduction in medical consumption (e.…
Self help interventions are useful in preventing work-related fatigue in coach drivers in the peak season.
In vulvar cancer patients with a macrometastasis in the sentinel lymph nodes, chemoradiation is as effective as an inguinofemoral lymphadenectomy, but is associated with less treatment-related morbidity.
We hypothesize that the addition of the newly developed web-based VCM to the exisiting decision aid will improve the support offered to patients in their decision-making process (improvement of disease-specific knowledge, feeling informed, and value…