129 resultaten
Chronic heart failure (CHF) is a clinical syndrome resulting from a decreased cardiac output, insufficient to maintain adequate tissue oxygenation. Eventually, inadequate tissue oxygenation will lead to pathological alterations, especially at the…
The implementation of the delirium part of the Vulnerable elderly project will improve when nurses have completed an e-learning tool regarding delirium care for elderly patients.
A levonorgestrel releasing intrauterine system (LNG-IUS) and endometrial ablation are two frequently used methods for the treatment of menorrhagia, of which the first can be applied by a general practitioner or a gynaecologist, whereas the second is…
Based on current literature we hypothesize that mindfulness based stress reduction training reduces psychological distress and improves 'positive mental health' in medical interns. Possibly MBSR can prevent psychological distress in the…
1. Describe concomittant electrical activation of endocardial and epicardial layers of atrium that have been shown in animal models to be dissociated, and to be involved in the perpetuation of AF; 2. Describe with a density mapping catheter the…
Ocular surface inflammation plays a pivotal role in dry eye and possibly in blepharitis. We hypothesize that the quantity of pro-inflammatory cytokines in tears and the expression of markers of inflammation on conjunctival cells are increased in…
1. Inhaltion of tobramycin containing aerosols using the INeb® in the TBM mode is less effective as inhalation of in the TIM mode; 2. The amount of deposition is correlated to the systemic Area Under the Curve of tobramycin after inhaltion of…
Does heated oxaliplatin reduce the acute peripheral neuropathy complaints in patient with a colorectal carcinoma.
1. Currently, there are a wide variety of therapeutic techniques for specific patients and certain psychological problems. The guidelines on mental health care focus only on the specific therapy factors. In addition to these specific therapy factors…
Nowadays after every venous treatment some form of compressive treatment is prescribed. Its use has been proven for surgical interventions, but is unclear for EVLT. Patients often think of wearing of these stockings as a burden.Therefore we will…
The primary objective is to quantify the learning process of self infusion and the self infusion procedure.
Intranasal administration of cobalamin can be used as an alternative for the standard intramuscular injection of cobalamin in cobalamin deficient patients.
To evaluate the impact of three different implementation strategies for implementing IBSM in current clinical practice, we have proposed the following three hypotheses: 1. Hypothesis 1 (Reach): More general practices will participate in IBSM in the…
The aim of the study is to compare the effectiveness of tocolysis with Nifedipine or Atosiban in pregnant women with threatened preterm labour with a gestational age between 25 – 34 weeks. We will look at neonatal mortality and morbidity, duration…
A constant Hb concentration will improve the quality of life of patiënts with a chronic need for bloodtransfusions.
Interferons (IFNs) are a family of cytokines which have important antiviral and antiproliferative properties. They also play an important role in immunomodulation. Type I IFNs have been implicated in autoimmune diseases, including systemic lupus…
The self-help intervention Happy@Work will reduce symptoms of depression. The self-help intervention Happy@Work will be cost effective.
The objective is to investigate the patterns and processes of change in Acceptance-Based Behavioural Therapy (ABBT; Acceptance & Commitment Therapy + mindfulness) with chronic pain patients having high levels of psychological flexibility.…
1. Measure DNIC and offset analgesia in neuropathic pain patients; 2. Compare DNIC and offset analgesia in chronic pain patients with DNIC and offset analgesia in healthy volunteers; 3. Assess the effect of oral tapentadol on DNIC and offset…
To determine the epidemiology, diagnosis and prognosis of enterovirus (EV) and parechovirus (HPeV) infection in Dutch children. Hypotheses: 1. EVs are one of the most important viral agents of infection in Dutch children; 2. EVs are the major cause…