146 resultaten
To test the effectiveness of a self help booklet without therapist guidance vis-à-vis a psycho-education brochure for adult problem drinkers in the general population.
The induction of immunity might be slower in older persons than in younger individuals. This could influence the occurence of adverse events induced by the vaccine.
We hypothesize that treatment with peppermint oil will lead to a greater symptom (especially abdominal pain) reduction in IBS patients compared to placebo. This will lead to a higher total percentage of responders (as defined by FDA/EMA…
The administration of propranolol will inhibit the increase in dermal blood flow (DBF) induced by capsaicin application.
The present study aimed to improve the performance of the A-DIVA scale by identifying predictors other than those included in the original scale. A modified A-DIVA II scale will be created which is applicable in the total hospitalized population to…
Sympatho-adrenergic and hypercoagulable activity are enhanced in patients with chronic heart failure, partially mediated by common functional beta2-adrenergic receptor polymorphisms. Non-selective beta-blockers down regulate sympathetic activation…
Laparoscopic ileocolic resection may be more effective than infliximab treatment in recurrent Crohn´s disease located in the terminal ileum improving quality of life and reducing costs.
TIPS using covered stents will be equally or more effective, cost-effective and safe as/than endoscopic treatment in the secondary prevention of gastro-esophageal variceal bleeding.
To investigate the impact of an open label non-mandatory switching strategy from Enbrel to Benepali on drug survival, effectiveness and safety in a controlled cohort study of RA, PsA and SpA patients in daily practice.
Subcutaneous immunoglobuline therapy is as effective as intravenous immunoglobuline therapy in maintaining muscle strength in patients with multifocal motor neuropathy
Vitamin D plays an integral role in calcium and phosphorus homeostasis. A low vitamin D status can occur as a result of reduced synthesis due to lack of sun exposure, decreased intake or absorption, increased hepatic catabolism, or decreased…
Sunitinib, when given in a high-dose, intermittent schedule, may exhibit improved efficacy in patients with recurrent GBM with an acceptable toxicity profile, compared to lomustine.
Implementation of Syncope Algorithms (SAs) in the Netherlands will increase diagnostic yield, avoid unnecessary admissions and improve quality of life (QoL) by offering timely diagnosis & treatment
We hypothesize that, asymptomatic patients with severe aortic stenosis, receiving an aortic valve replacement have a better quality of life compared to patients without aortic valve replacement.
Our hypothesis is that our gradually progressive protocol offers advantages with respect to the eccentric protocol based on the protocol of Alfredson (gold standard). We expect that, because this protocol is more individualized, less pain during the…
The primary aim of the study is to investigate patient characteristics that predict (differential) treatment response across MBT and ST. In addition, mechanisms of change in MBT and ST will be examined. Furthermore, the (cost-)effectiveness of MBT…
A. COMET as an additional transdiagnostic intervention focusing specifically on low self-esteem increases the effectiveness of mentalization based treatment in patients diagnosed with borderline personality disorder. B. This increased effectiveness…
Describing the pharmacokinetics of nimodipine, especially the variability of bio-availability orally administred nimdipine.
Collaborative stepped care for anxiety disorders in primary care is cost effective compared with Care As Usual.