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Based on previous studies, we will expect that ambroxol improves neurological manifestations in patients with GD3.
Does suppletion of vitamine D3 (cholecalciferol) have an effect on the systolic blood pressure in hypertensive, vitamin D insufficient patients? 1. H0 hypothesis: there is no effect on the systolic blood pressure; 2. H1 hypothesis: the systolic…
To study the effect of the interaction of cyclooxygenase-2 (COX-2) inhibition (started preoperatively and continued 5 days into the postoperative period) and extended local anaesthetic blockade via paravertebral block on postoperative central…
To evaluate whether a dietary advice of green vegetables, beef and whole dairy products during six months including standard supportive care can decrease the TSH-level compared to standard supportive care alone in children aged 1-18 years with…
In the present study we will investigate the pharmacokinetic profile of three doses of sublingual testosterone, and measure subjective and physiological measures of sexual functioning in healty premenopausal women. The lowest effective dose of…
AN-PEP helps to digest gluten in vivo.
The goal of this trial is to investigate whether (and at which dose or ratio) CBD has a modulating effect on the psychotropic effects of THC by comparing the effects of THC to the combination of THC with CBD in a range of ratios. Simultaneously,…
RhDNase can liquefy mucus in children with an atelectasis during mechanical ventilation, resulting in improved mucociliary clearance, less mucus retention and less airways obstruction, thereby enhancing the rate of resolution of an atelectasis.…
In the present placebo controlled study we will investigate the influence of valence on attention when viewing visual erotic stimuli. Especially when under the treatment condition of testosterone with sildenafil. In addition, we will investigate the…
An online intervention will be an effective intervention for treating affective symptoms in pregnancy and their complications by reaching more women and making therapy easier accessible
In the RIO study programme, the efficacy of rimonabant was examined. The next step is to assess the use of rimonabant, its safety and effectiveness in daily practice. In daily practice people also have other diseases, may use other medication and…
We hypothesize that oral glucose intake and consequently the endogenous induced hyperinsulinemia will lead to insulin-induced microvascular dilatation in healthy normotensive subjects. Furthermore, we suggest that the insulin-mediated microvascular…
The purpose of this study is to evaluate the efficacy of oral ibandronate (versus placebo) added to the standard radiotherapy regimen for painful bone metastases to reduce pain, to reduce the need of analgesics, and to reduce skeletal-related events…
A 7-day course of antibiotic treatment is non-inferior to a 14-day course in febrile urinary tract infection.
We hypothesize that PHA-022121 will be more effective in both the treatment and prophylaxis of acute angioedema attacks in patients with acquired C1-inhibitor deficiency when compared to placebo.
Conditioning with hydrocortisone will result in altered endogenous cortisol during rest in the evocation phase.
Pelvic floor muscle spasms resulting in chronic pelvic pain may occur as a primary event or secondary to a physical, psychological or pathological factor. First-line treatment consists of pelvic floor physiotherapy. When first-line treatment fails,…
Treatment with a probiotic dairy product releives symptoms in Irritable Bowel Syndrome patients. It also improves quality of life of the patients, and has an positive effect on the composition of the microbiota. Cytokine stimulation profiles will…
Different processing of milk products will have impact on metabolic availability of amino acid
5 and 10 grams of a protein hydrolysate effectively increase insulin secretion and lowers plasma glucose levels after a carbohydrate load in type 2 diabetes mellitus (DM-2)