871 resultaten
To demonstrate a 25% increase of docetaxel in tumor tissue after intravenous administration of CriPec® docetaxel compared to Taxotere®.
A vaccumcurettage in persistent trophoblactic disease decreases the number of chemotherapy cycles needed to obtain normalisation of the hCG level.
A tailored web application for THA patients based on three patient subgroups is a) usable for patients and care providers, and b) valuable for patiens by improving post-surgery support.
We hypothesize that offering patient after general surgery water ice cream will reduce the side effects of sore throat and foul smell and in general increase the quality of recovery.
The purpose of the activity and heart rate monitor is to measure and track movement (acceleration) and heartbeat, and derive a number of health-related parameters, which can serve as basis for behavioral change programs leading to e.g. a healthier,…
We hypothesize that the CPA Talking-with-children-intervention will have a beneficial effect on the mental health and quality of life of maltreated children. We expect that children who participate in the CPA investigation (CPA Talking-with-…
We hypothesize that it is possible to culture circulating tumor cells obtained by leukapheresis into organoids.
It is expected that the urinary and serum level of intestinal fatty acid binding protein (I-FABP) and the urinary level of Claudin-3 have prognostic relevance for early identification of patients at risk for intestinal ischemia-related morbidity or…
1. Verbeteren van de overleving in vergelijking met de eerdere protocollen van de SKION, in het bijzonder ALL-9 and ALL-10. Doelstelling is om therapie te verminderen voor een deel van de patiënten (TEL/AML1, Down syndroom, geïsoleerd slechte…
Patients with a BMI > 30 kg/m2 in the ICU have a higher incidence of pressure ulcers and wound infections in the ICU compared with patients with a BMI 18-25kg/m2. They develop them sooner during admittance and the severity and time to…
Secondary attack rates of SARS-CoV-2 will differ when stratified for the age of the index case.
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Metabolically healthy obese subjects are characterized by increased adipose tissue expression of genes involved in triglyceride storage, lower inflammatory changes and lower ectopic lipid accumulation compared to metabolically unhealthy subjects.…
Glycocalyx volume is diminished in subjects with premature atherosclerosis.
1. Nandrolone decanoate injection reduces muscle loss in the upper leg during immobilisation 2. Leucine supplementation during immobilisation of the knee reduces muscle loss in the upper leg
Tumor-positive lymph nodes in patients with early EAC can be accurately detected through a sentinel node procedure.
Frequently people experience nausea and vomiting following surgery. There are several pharmacologic interventions possible; there is no rational evidence-based approach available. In this study the current therapy regaring PONV and its efficacy in…
We hypothesize that podocyturia is an early marker of ongoing renal damage during angiogenesis inhibition.
Quantification of mast cell density in human volunteers will inform future interventional studies that impact mast cell proliferation and/or turnover
1. When patients visit their GPs with unexplained complaints it is cost effective to follow a watchful waiting strategy of four weeks before ordering laboratory tests; 2. A systematically developed quality improvement strategy, based on barriers…