156 resultaten
An upfront RBCT aiming at low-normal Hb levels will ameliorate anemia-caused tumor hypoxia-related resistance to chemotherapy before the start of chemotherapy and may decrease secondary anemia-induced endogenous release of cytokines like VEGF,…
Donor-specific antibodies form a significant barrier in transplantation of highly pre-sensitized dialysis patients. Increased waiting time is associated with increased morbidity and mortality among these patients. Thus, there is a need to further…
The EEG profile in responders to methylphenidate will be differ from the EEG profile in non-responders to methylphenidate (i.e. higher total power, increased theta/beta ratio and theta/alpha ratio).
It is our hypothesis that a combined life style intervention of exercise and weight loss will result in a reduction of pain and improvement of function of the affected hip joint, which will postpone a chirurgical intervention.
The hypothesis of this study is that the pubertal delay in transsexual adolescents, induced by treatment with GnRH analogues, will cause a difference in the development of brain structures and brain function between transsexuals and age matched…
The primary objective of the study is to study the safety of MMR booster vaccination in JIA patients by measuring JIA disease activity and the occurrence of measles, mumps or rubella infection. The next primary objective is to evaluate the efficacy…
1. Cognitive behavioural group therapy is more effective than no intervention in prevention of social anxiety and related psychological problems; 2. Computer-based BiasRetraining is more effective than no intervention in prevention of social anxiety…
Subcutaneous immunoglobuline therapy is as effective as intravenous immunoglobuline therapy in maintaining muscle strength in patients with multifocal motor neuropathy
Describing the pharmacokinetics of nimodipine, especially the variability of bio-availability orally administred nimdipine.
Atomoxetine will be effective in reducing symptoms of inattention and overactivity in children and adolescents with ASD.
A two month distraction period results in similar clinical beneficial effects as a three month distraction period.
Obtain transient temperature data of the skin, core and wound surface during orthopedic back surgery in order to validate the numerical model of Severens for this type of surgery.
ETMI increases the detection rate of early neoplasia in BE patients with 40% or more compared to standard video endoscopy
1. To develop (cost-) effective implementation strategies which are feasible in daily practice; 2. To test the guidelines in a multicentre effectiveness trial; 3. To develop general quality indicators with appropriate measuring tools for diagnostic…
MPS I patients can be treated with Aldurazyme safely and effectively.
The hypothesis of the present study is to demonstrate that detection of a particular pattern (e.g., persistent vs. non-persistent) of myocardial (alpha)V(beta)3/5 expression by scintigraphy imaging at 3 and 8 weeks after MI can be used to determine…
1. It is hypothesized that participation in the Active plus program contributes to an increase in physical activity behaviour among older adults; 2. Additionally receiving physical and social environmental information results in an extra increase…
Locoregional anesthesia does not work as well in patients with the Ehlers-Danlos syndrome as in people who do not have this syndrome.
The primary aim of our study was to test the feasibility and safety of exclusively intramuscular, and combined intramuscular/intra-arterial delivery of Bone marrow Mononuclear Cells (BMC) in patients with advanced without conventional options for…