44 resultaten
Het doel van de studie is het bestuderen van de functionele hypothalame response op glucose ingestie in obese proefpersonen.
De studie bestaat uit 2 delen. Deel 1: Evaluatie van het seksueel functioneren van MRK(H) vrouwen, het seksueel zelfbeeld, psychologisch en relationeel functioneren van deze vrouwen en het seksueel functioneren van hun partners en vergelijken met…
Het doel van deze studie is het onderzoeken of de verschillen in DNA methylatie, die gezien zijn bij zij die blootgesteld zijn tijdens de zwangerschap aan de Nederlandse Hongerwinter,door worden gegeven aan een volgende generatie.
Het screenen van twee verschillende formuleringen van de recombinant malaria vaccin PfLSA-3-rec, één adjuvant met aluminium hydroxide en één met Montanide Isa 720, door zowel de veiligheid en het immunogeniciteitsprofiel (fase I) van elke…
The main clinical challenge remains to identify patients who may benefit from aggressive local treatment (stereotactic radiotherapy, SBRT) of soft tissue oligometastases: for which patients can systemic treatment be postponed? Patients who are…
A subset of rheumatoid arthritis (RA) patients harbour antibodies against several post-translational modifications and are frequently positive for rheumatoid factor. The exact pathophysiology of the development of the autoantibody response and of RA…
SARS-CoV-2 is present in the cerebrospinal fluid of COVID-19 patients with acute respiratory failure
The aim of this study is to assess whether the use of the IncoSense Smart leads to improvement in efficiency of incontinence care, better quality of life of the clients and reduction of the cost.
A disease control of 60% is expected and will be clinically relevant with a lower reference bound of 45%.
It was hypothesized that comparing the course of uveitis of individual eyes with respect to inflammatory activity and visual acuity (VA), and the impact of particular therapies, to already available data about course and outcome from other patients…
We hypothesize that FMT from a healthy donor will modulate the microbiome of the pouch of patients with ulcerative colitis, and will thereby resolve the inflammation of the pouch.
Transvaginal implantation of ABS system reduces the risk of infection.
We hypothesize that higher EC within the FPN is a predictor of better EF. Furthermore, we hypothesize that multilayer centrality is a better predictor of EF than monolayer centrality.
Because the aim of this observational study is to obtain insight in the nutrient and fluid intake, and nutrient and biomarker concentrations in the blood in patients with ischemic stroke, the focus will be on descriptive statistics and there will be…
The gastric balloons are expected to remain in the stomach for approximately four weeks, after which they burst and are fecally excreted. It is further hypothesised that intragastric balloons can provide a surrogate stomach fill, inducing an…
Multi-centre open label clinical trial.
Simvastatin (an HMG-CoA reductase inhibitor) induces apoptosis in vitro and sensitizes the myeloma cell to chemotherapy. This is the first clinical trial to test if in vivo there is the same sensitization in relapse or refractory multiple myeloma.
Oral ondansetron reduces the proportion of referred children to a (paediatric) emergency department when added to oral rehydration therapy compared to oral rehydration therapy alone.
1. Welke rokers hebben baat bij welke transmurale “stoppen-met- roken- interventiestrategie”?; 2. Wat zijn de effecten van de verschillende “stoppen-met- roken- interventiestrategieën”?