It was hypothesized that comparing the course of uveitis of individual eyes with respect to inflammatory activity and visual acuity (VA), and the impact of particular therapies, to already available data about course and outcome from other patients…
ID
Bron
Verkorte titel
Aandoening
Non-infectious uveitis for at least 3 months.
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Change of visual acuity between entry and 12 months.
Achtergrond van het onderzoek
Uveitis is a potentially sight threatening eye disease. There are no clear guidelines or studies directing therapy. Based on cohort studies regarding outcome in subentities of uveitis and clinical experience, therapeutic decisions are made on an ad hoc basis during, and adapted to, the course of the invidual eye’s uveitis. A predictive model has been built and internally validated using cohort and individual disease activity and therapy to predict the resulting visual outcome. The objective is to study the effect of the availability of a predictive uveitis model in the clinical setting on the 1 year visual outcome of patients.
Doel van het onderzoek
It was hypothesized that comparing the course of uveitis of individual eyes with respect to inflammatory activity and visual acuity (VA), and the impact of particular therapies, to already available data about course and outcome from other patients would be of better predictive value than demonstrated, as yet, by identifying group-specific phenotypic and genotypic risk factors.
Onderzoeksopzet
0 and 12 moths.
Onderzoeksproduct en/of interventie
Introduction of information of a predictive model.
Publiek
Postbus 70030
Rene Wubbels
Rotterdam 3000 LM
The Netherlands
+31 (0)10 4023449
ROI@oogziekenhuis.nl
Wetenschappelijk
Postbus 70030
Rene Wubbels
Rotterdam 3000 LM
The Netherlands
+31 (0)10 4023449
ROI@oogziekenhuis.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
- Non-infectious uveitis for at least 3 months.
- Age ≥ 18 years.
- Informed consent.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
- Major eye condition preventing any VA improvement or reduction (such as end stage glaucoma, end stage corneal diseases, end stage macular degeneration).
- Suspected or proven infectious uveitis.
- Masquerade syndromes (such as intraocular B cell lymphoma).
- Patients for whom all data of the first year since onset of their uveitis are missing.
- Patients for whom, since onset of their uveitis data from a substantial period of time (> 3 years) are missing.
Opzet
Deelname
Voornemen beschikbaar stellen Individuele Patiënten Data (IPD)
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL6983 |
| NTR-old | NTR7172 |
| Ander register | NL63970.078.17 : OZR-2014-21 |