125 resultaten
The flavonoid-drug interaction could potentially lead to higher nintedanib absorption by the gastro-intestinal tract. This would cause higher systemic bioavailability and lower local gastro-intestinal drug concentrations. Furthermore, inter-patient…
Adding specific components designed to target three risk factors for child maltreatment (parental stress, parental anger, and post-traumatic stress symptoms) to an evidence-based home visiting program alleviates these specific risk factors.
exercise improves social functioning, quality of life and decreases symptom severity
Our hypothesis is that growth hormone threatment in adults with Prader-Willi Syndrome will improve their metabolic and cardiovascuar health, thereby resulting in a reduced mortality.
The post-prandial rise in total amino acid, proline and glycine concentration following a single bout of resistance exercise will be the highest in the 20 gr whey combined with 10 gr collagen compared to all other test drinks
Overall, diagnostic accuracy will be lower on subjected-to-bias than on not-subjected-to-bias cases, but the difference in accuracy will be smaller in the group of physicians with higher knowledge of critical diagnostic features. Overall, the…
Polystyrene sulfonate shows an in-vitro binding interaction with amitriptyline, causing 70-80% binding of amitriptyline to polystyrene sulfonate. The hypothesis is that polystyrene sulfonate binds to amitriptyline when taken simoultaneously in…
The intended research aims to evaluate whether a better suppression of adrenal androgens, so a better hormonal setting, can be achieved by changing the time of the highest dose in the morning or in the evening.
1. The addition of moderate positive end-expiratory pressure (PEEP, 7.5 cmH2O) to high inspiratory fractions of oxygen can either improve oxygenation or reduce respiratory rate, or both, in patients with severe Covid-19 pneumonia 2. The application…
Using inhaled volatile anaesthetic agents as the primary sedative during mechanically ventilation in patients with COVID-19-associated ARDS improves gas exchange and ventilatory support requirements
Flexible RPD's have a higher impact on OHRQoL compared to acrylic RPD's.
Primary hypothesis is whether patients with a PTSD the distraction of a positive emotional valence will be more effective in decreasing the vividness and emotionality of a traumatic memory compared to distraction with a neutral task or exposure only…
2C-B generates distinct acute and subacute effects from Psilocybin and placebo
The hypothesis of this study is that implementation of an evidence-based management algorithm to standardize care will improve the level of care, lower the complication rate and improve the quality of life for patients with chronic pancreatitis.
It is expected that patients prefer the AFO with the best efficacy, and that the preference is reliable at the moment of AFO fitting.
In T2DM patients with DKD, an acute oral sodium load results in less renal sodium excretion than in healthy individuals and non-DKD T2DM, which can be restored by administration of a GLP-1 receptor agonist.
Cognitive remediation focused on executive functioning for patients with bipolar disorder improves executive functioning on (1) personal goals in daily life, and (2) general well-being. Exploratory hypotheses: - Cognitive remediation focused on…
We hypothesize that giving feedback to healthcare providers on the performance of their own hospital improves processes of care and leads to better outcomes.
It is expected that differences in energy density of the study products will modulate the protein digestion profile of dairy proteins in elderly
1. DKD patients are salt-sensitive due to a decreased sodium buffering capacity (damaged ESL). As a consequence a high sodium diet will lead to water retention, resulting in increased ECF, body weight and blood pressure. 2. CKD patients are salt-…