149 resultaten
Primary hypothesis is whether patients with a PTSD the distraction of a positive emotional valence will be more effective in decreasing the vividness and emotionality of a traumatic memory compared to distraction with a neutral task or exposure only…
Effective SCS affects brain activity that is related with chronic pain
A 4-month WFPD H0: has no effect on the levels of serum uric acid in patients with gout, hyperuricemia and abdominal obesity in comparison with usual care. H1: results in decreased levels of serum uric acid in patients with gout, hyperuricemia and…
In the first of two substudies, we test the hypothesis that in healthy individuals without ELS, hydrocortisone will be effective in enhancing stress adaptation and extinction learning in an experimental model of exposure therapy, while it is not in…
The main objective is to evaluate the efficacy and safety of phenytoin cream in patients with neuropathic pain due to CIAP
The flavonoid-drug interaction could potentially lead to higher nintedanib absorption by the gastro-intestinal tract. This would cause higher systemic bioavailability and lower local gastro-intestinal drug concentrations. Furthermore, inter-patient…
Hypothesis 1. The slopes of improvement are significantly stronger during ST than during control conditions (baseline, ST-preparation, communication training, follow-up). Hypothesis 2. The slopes of improvement in the sequence ST - Communication…
Treatment with chloroquine or hydroxychloroquine of adult patients admitted with moderate to severe COVID-19, a NEWS-2 score ≤5, reduces the proportion of patients who show progression of their disease defined as a NEWS-2 score ≥ 7(22), admission to…
Due to the difference in mineralocorticoid characteristics between prednisolone and dexamethasone, it is hypothesized that dexamethasone will have a greater effect then prednisolone, especially when assessing neurocognitive function and blood…
• Overall, the patient-tailored PROfeel lifestyle advice will be more effective in reducing patients’ fatigue severity than the generic dietary advice. • Overall, the patient-tailored PROfeel lifestyle advice will have a more positive effect on…
ICS can be safely withdrawn in T2-low asthma patients with obesity in secondary care (i.e. without loss of asthma control).
Smart energy meter data used in a monitoring system to alert users when out-of-the-ordinary activity is detected, may improve health-related quality of life and perceived safety of community-dwelling older persons and their informal care providers.
Foods that are consumed quicker, with a faster energy intake rate, will lead to higher daily energy intake, independent of food processing level.
We expect higher bioavailability of seaweed types containing more inorganic iodine, compared to seaweed types containing more or organic iodine.
1. DKD patients are salt-sensitive due to a decreased sodium buffering capacity (damaged ESL). As a consequence a high sodium diet will lead to water retention, resulting in increased ECF, body weight and blood pressure. 2. CKD patients are salt-…
To test the hypothesis that apathy after STN DBS may be reversed by switching the activated contact on the DBS-electrode from a ventral to a more dorsal contact.
Tumour cell disruption by radiation generates a surplus of neo-antigens that enhances the effect of immunotherapy in solid malignancies as well as malignant lymphomas. The hypothesis is that the combination of immune checkpoint inhibitors and…
We hypothesize that the combination of LEF/HCQ significantly and safely inhibits activity of primary Sjögren’s syndrome and molecular fingerprints will allow prediction of therapy response as well as identification of pathways that confer lack of…
De studie heeft als doelstelling de verschillen in maaglediging en eiwit opname van caseïne met verschillende productmatrix (mineralensamenstelling) te meten.
The higher hardness/protein density of protein gel would delay gastric emptying and protein hydrolysis in humans; MRI technique can used to monitor gastric digestion (in this case: protein hydrolysis) in humans.