146 resultaten
To investigate the acute responses occuring in the esophageal mucosa of EoE patients after local allergen provocation
We hypothesize that acetaminophen and nimodipine have a positive influence on postictal phenomena after ECT induced seizures and this is mediated by a reduction of postictal cerebral hypoperfusion.
Trifluridine is primarily metabolized through degradation by thymidine phosphorylase to the inactive metabolite 5-(trifluoromethyl)-uracil (FTY) without any involvement of the cytochrome P450 enzyme system. The primary route of excretion of…
The PSQI score is significant lower in the intervention group as compared to the placebo group after 3 weeks of oral intake of the test product.
We expect both types of tactile cueing (open- and closed loop) to be feasible and effective, with tactile cueing being preferential over auditory cueing.
We hypothesize that TIPS placement has an significant effect on drug metabolism and bile acid metabolism.
1. Serum potassium in hemodialysis patients (CKD stage 5D) is mainly influenced by alterations in the internal potassium balance. 2. Higher dialysate potassium in CKD-5D increases the potassium erythrocyte concentration as proxy for TBK. 3. The…
Dental intra-oral bitewing radiography with protable X-ray equipment is non-inferior to btewing radiography with wall mounted X-ray devices
In the current study, we will construct utility functions of two opioids, tapentadol and oxycodone, to assess the benefit/harm ratio of these drugs. To that end we will perform a PK PD study in healthy volunteers
The purpose of this study is to investigate the effect of recorded music on surgical task performance and mental workload in a simulated setting. The study hypothesis is that preferred music will improve surgical task performance and decrease mental…
A relationship exists between a pharmacologic effect of ENX-201 and the plasma concentration
Sleep deprivation induces impaired driving behavior, decreased cognitive function and lower pain thresholds
We hypothese that the health care for hand prosthesis users can be improved in terms of cost-effectiveness.
Primary hypothesis: We hypothesize that congruent appetite and food intake will be higher after exposure of macronutrient-related odours compared to low-calorie odour. Secondary hypothesis: We hypothesize that specific macronutrient preference will…
Not applicable
we hypothesize that thermal comfort and sensation will stay within similar ranges in both conditions (based on a previous study);
For over a decade, adults suffering from Raynaud’s phenomenon secondary to systemic sclerosis, have been supplied with textiles (gloves, socks, shirts and pants) which contain silver fibres. In general, patients state to experience benefit from…
Overall: when kidney function deteriorates, regulation of the potassium balance in response to potassium loading switches from renal to non-renal mechanisms. 1. Serum potassium in CKD is mainly influenced by alterations in the internal potassium…
Appropriate use and prescription of a lower limb prosthesis for people with leg amputation through or above the knee, can increase the efficiency of the integrated care around the leg prosthesis.
To explore the effects of CST-101, CST-103, and CST-109 on CNS functions that are relevant to neurodegenerative disorders.