306 resultaten
We therefore hypothesize that FABP/Claudin levels may be used as a diagnostic tool for the identification of intra-abdominal injury necessitating surgery and as a prognostic marker for the development of SIRS/MOF (and morbidity and mortality) in…
Peri-operative interventions improve fragile patients functional health status, reduce complications and length of stay in hospital after elective surgery.
We hypothesise that the intervention group will significantly improve detachment by increasing daily physical activity and relaxation, compared to the control group receiving usual care (minimal intervention or company's current health…
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Training medical specialists in consultation skills focused on MUPS patients improves the specialistic care for these patients in terms of illness worries, course of symptoms and daily functioning and reduces the medical costs for this patient group…
Elaborate training will have a positive longterm effect on the longitudinal measurement properties of the PDASII.
The percentage of curatively treatable metastatic disease after surgery for primary colorectal cancer can be increased by means of optimizing follow-up of colorectal carcinoma. Intensifying the follow-up by increasing frequency of CEA measurements…
Establishing the cause of pleural disease often is a great challenge. Definitive diagnosis of pleural disease needs histological confirmation in most cases. Clinical suspicion of malignancy often indicates prompt use of invasive procedures like…
1. There is wide variability in thrombogenic and atherogenic risk factors, SCORE-score and degree of atherosclerosis assessed by calcium score and IMT/plaque in patients with unprovoked PE; 2. Patients with unprovoked PE who develop an arterial…
1. Has tailored information on hepatitis B prevention more effect on test behaviour than generic information? 2. Does 'cultural tailored' information on hepatitis B prevention have more effect on test behaviour than tailored information?
It is hypothesised that energy related behaviours and work engagement will improve as a result of the intervention. Overweight will be prevented as a result of the improvement in energy balance related behaviours. In addition, work related measures…
HIV-induced immune activation through intestinal bacterial translocation can be modulated by statins.
S(+)-ketamine influences resting state fMRI in a dose-dependent fashion.
Before we focus our research on TMS-EEG experiments in epilepsy patients, we first aim to learn more about the characteristics and intra-subject variability of the TMS-EEG and MEP response in healthy subjects. In addition, we will evaluate if TMS-…
The hypothesis is that the prevalence of heart failure is underestimated in Dutch nursing homes. In addition it is hypothesized that residents with heart failure experience a lower quality of life, have a higher degree of care dependency and have…
One of the challenges in paediatric anaesthesia is to minimize distress for children in the operating room environment and to facilitate a smooth induction of anaesthesia. Pre-anaesthetic medication reduces the risk of adverse psychological and…
The most important problem after kidney transplantation is the occurrence of chronic interstitial fibrosis (IF) and tubular atrophy (TA), which leads to graft loss. Tacrolimus induced nephrotoxicity importantly contributes to the development of IF/…
Accumulating data from both patients and animal models indicates that imbalances in the composition of the gut microbiota are related to obesity and its associated diseases However, the exact role of the microbiota and the mechanism mediating its…
Major depressive disorder (MDD) is projected to rank second on a list of 15 major diseases in terms of burden and is highly recurrent in nature. Accordingly, efforts to reduce the disabling effects of this chronic condition should shift to…
To evaluate the usefulness of the VascuLuminator for venipuncture for blood withdrawal in children and to find out for which type of patients the VascuLuminator is mainly used.