1616 resultaten
We hypothesise that exercise may reduce risk of breast cancer, either directly or indirectly through a reduction in abdominal fat mass, by favouring the sex hormone profile and decreased insulin. Because the association between breast cancer and…
The overall objective of this study is to assess safety of AG-348 and provide proof of concept of the efficacy of the drug in SCD patients. Based on currently available data, we hypothesize that the benefits of treatment of sickle cell disease…
In non-COVID-19 patients with pulmonary embolism a prevalence of up to 70% of concomitant symptomatic or asymptomatic deep venous thrombosis has been reported. Physicians experience an exceptionally high prevalence of pulmonary embolism in COVID-19…
The open preperitoneal approach in inguinal hernia repair might have the benefit of a mesh in the preferred space without the disadvantages of an endoscopic procedure.
residual thyroid function is altered by short term oral antibiotic treatment in subclinical hypothyroid subjects as compared to healthy controls.
1. The primary objective of this study is to investigate whether nocebo effects on cowhage-evoked itch can be induced by verbal suggestion. We hypothesize that the verbal suggestion that the solution applied is an ‘itch solution’ will induce higher…
Patients with new-onset or recurrent AF have an altered myocardial sympathetic activity. The quantification of sympathetic activity with 123I-mIBG scintigraphy, as well as its change over time after restoration of sinus rhythm, can be used to target…
Observational study
It is expected that the use of the MFB intervention will improve subjective cognitive functioning.
With this study we aim to disentangle mindfulness and placebo effects on pain. We investigate how decentering (a core component of mindfulness) and positive treatment expectations (a core component of placebo effects) interactively contribute to…
Similar or better fixation, migration and functional outcomes compared to other existing techniques
We hypothesise that the health behaviour of pregnant women is influenced by the measures to prevent the spread of COVID-19. It is not clear however, if it is positively affected (because of having more time, providing online options, creating a…
To determine the feasibility of the measurement protocol of a large prospective longitudinal study to describe the exercise capacity and physical functioning of critical illness survivors up to 5 years after discharge from the ICU.
Our hypothesis is that critical ill COVID-19 patients suffer more from their own immune response against the virus, than from the viral infection itself. Alkaline phosphatase (RESCAP®) has proven to reduce SIRS reactions by neutralizing the…
We expect the “movement with pain” program will result in a reduction in disability, improved perceived recovery, improvement of psychological wellbeing and increase in physical condition. Moreover, we expect that a combination of the amount of…
The hypofractionated regimen of 19 fractions will result in an increase of relapse free survival by 10 % with the same acute and late toxicity as the standard fractionation of 39 fractions.
Hypertension can be prevented, or substantially delayed, by a temporary and early anti-hypertensive intervention with an ACE inhibitor in persons at high risk for future hypertension and hypertension related complications.
The prevalence of Growth Hormone Deficiency in Autoimmune Thyroid Disease is higher than in the general population
Prevention of radiotherapy side-effects by early hyperbaric oxygen administration.
RR with prompting results in a higher rate of self-initiated toileting and a decrease in urinary/faecal accidents. For children who do not attain continence with RR and prompting alone, an add-on restoring procedure will result in a higher rate of…