226 resultaten
Combining FOLFIRINOX chemotherapy and stereotactic radiotherapy can lead to better regional tumor control and better overall survival in patients with locally advanced pancreatic cancer.
The aim of the study is to explore the relation between frailty, functional status and other patient characteristics and adverse outcomes as functional decline, length of stay, admissions and mortality. Frailty is multifactorial and is known to be…
Primary objective: To determine the safety of once daily inhalation of the recommended daily dose of tobramycin with the Akita® and the PARI-LC® Plus nebulizer in patients with CF. Systemic absorption can be used as surrogate parameter for safety.…
* Mortality among adult ischaemic and intra-cerebral haemorrhagic stroke patients admitted to an Intensive care Unit (ICU) is higher compared to other critically ill populations, subdivided into predefined diagnostic groups, over time and regardless…
The prevalence of disinhibited behavior is high in institutionalized people with the behavioral variant of frontotemporal dementia. Disinhibited behavior is associated with reduced well-being of residents and is experienced as an important challenge…
We hypothesize that the deformation-volume loop will help to identify the consequences of aortic stenosis and the changes in functionality after aortic valve replacement (AVR)
Patients suffering from high risk or relapsed leukaemia or high risk MDS can only occasionally be cured with conventional chemotherapy. Allogeneic stem cell transplantation (allo-SCT) has substantially improved the outcome of such patients due to a…
We hypothesize that DM1 is accompanied by impairments in whole-body and/or muscle metabolism.
In this current research we investigate whether the GPS is a reliable and valid screening instrument for PDs in geriatric medicine, and therefore could be used as a supplement on the currently used assessment methods of the multi-problems associated…
Identify biomarkers in the stratum corneum which are suitable to assess the protective effect of sunscreens in vivo.
The module “Working with parents in creating a pleasant school” positively effects the attitudes, efforts and self-efficacy of teachers, parents, students in (jointly) counteracting bullying.
The TORCH screen is often requested by gynecologists, but there rarely is a clinical relevant outcome. Isn’t it better to reduce the test indications or the number of tested infections to make the test more cost effective and clinical relevant? And…
It is hypothesized that chicken eggshell membrane is effective in the regeneration of cartilage and/or immunomodulation (oral tolerance), and as such positively affects pain and stiffness in joints commonly affected in arthritis
Research question: To explore if Social Network Testing (SNT) for HIV is feasible and acceptable among men having sex with men with a non-Western migration background (MSM-NW), and if it reaches those who have never tested for HIV.
The primary objective of the study is to examine whether the WhiteTeeth app used by orthodontic patients aged 12 to 16 improves oral health behavior and oral hygiene. Primary outcomes of this RCT are dental plaque levels, gingival bleeding upon…
We hypothesize that clarifying the values of patients with incurable cancer without regular treatment options will empower patients and will create more effective patient-physician communication which helps to better attune communication to the…