233 resultaten
PD-L1 is up to now the only marker that has been validated for the selection of patients treated for non-small cell lung cancer who might benefit from the treatment with PD-1/PD-L1 inhibitors. Thus far, PD-L1 status is assessed with histology, being…
The COL3A1 polymorphism is a inheritable genetic defect, responsible for the increased susceptibility to pelvic organ prolapse in women.
Non invasive hemodynamic monitoring is as good as invasive monitoring
Knee OA is characterized by the presence of crepitus (knee sounds). Therefore, this device is able to record these sounds, while the subject is doing a knee movement, and screen for the presence or absence of osteoarthritis.
In the Netherlands, 90% of the patients with gout are managed by general practitioners but most research has been done in secondary care. In primary care there are questions on the clinical relevance of long-term uric acid lowering treatment of gout…
Several reasons for clozapine discontinuation are known, but the current evidence identifying patients who are at risk of discontinuation of clozapine is small and not always consistent. Also cultural differences may question if international…
We hypothesize that socioeconomic inequalities in diet quality are partly explained by differential dietary costs.
The aim of this study is to develop and validate an age-specific checklist that can help clinicians to identify elderly patients with personality disorders in need of highly specialized mental health care.
18F-FDHT PET/CT is expected to be a predictor of response in patients with metastasized castration-resistant prostate cancer to be treated with enzalutamide
A dual mobility cup with a small size head (22 mm) is more likely to result in intraprosthetic dislocation than a bigger size head (28 mm).
We hypothesise that the relations of total fat and fatty acid (FA) subtypes (SFA, MUFA, or PUFA) with CHD are modified by their food source. We aim to directly compare relations of FA subtype intake from dairy and meat with risk of CHD by using…
We hypothesize that storytelling (in the form of a sub-plot), concerning the effects of (un)healthy lifestyle on heart risk, in a popular Dutch TV show for children can cause sustainable positive lifestyle change. Furthermore, we hypothesize that…
HbA1c is still considered to be the most reliable indicator of the average blood glucose concentration over a longer period of time and therefore used as a guide for treatment of patients with diabetes mellitus (DM). But, HbA1c levels are influenced…
Short-term (1-year) results of renal transplantation are now excellent (over 95%). Long-term (10-year and longer) results are, however, still disappointing. Where most research has focused on immunosuppression and infections, we hypothesize that due…
Deep neuromuscular block has advantages over a moderate neuromuscular block in term of outcome (pain, respiration) but has otherwise no effects on the patient
Body weight has an effect at the trough concentrations of DOACs in patients.
E-PsEYE in comparison with usual care is cost-effective.