233 resultaten
Assess the safety and tolerability of single ascending Intravenous (IV) infusion doses of ABP-700
The primary objective of this study is to investigate if a specifically designed VR-game is able to activate the pathophysiological substrate associated with OCD in OCD patients, as opposed to healthy controls. This will be investigated by…
To evaluate if topical corticosteroid plus emollient cream is efficacious as topical corticosteroid applied twice daily in mild to moderate plaque psoriasis
Medtronic , Inc. is sponsoring the World-wide Randomized Antibiotic Envelope Infection Prevention Trial (WRAP-IT), a randomized, prospective, multi-center, single blinded, post-market, interventional clinical study. This study will evaluate the…
We hypothesize that patients with type 2 diabetes mellitus (T2DM) in the Netherlands have a lower prevalence of limited joint mobility compared to the literature (phase one). Diabetes patients with shoulder pain have shoulder muscle denervation, as…
We hypothesize that a single night of short sleep duration (4 hours), compared to normal sleep duration (8 hours) reduces metabolic flexibility, increases insulin resistance and thereby reduces HPA-reactivity. Furthermore, we hypothesize that a…
The aim of the study is to explore the relation between frailty, functional status and other patient characteristics and adverse outcomes as functional decline, length of stay, admissions and mortality. Frailty is multifactorial and is known to be…
* Mortality among adult ischaemic and intra-cerebral haemorrhagic stroke patients admitted to an Intensive care Unit (ICU) is higher compared to other critically ill populations, subdivided into predefined diagnostic groups, over time and regardless…
We hypothesize that the deformation-volume loop will help to identify the consequences of aortic stenosis and the changes in functionality after aortic valve replacement (AVR)
We expect youth in the intervention group to show greater improvements in change beliefs, empowerment, coping and self-worth and greater reductions internalizing and externalizing problems in comparison to youth in the control group.
A bounding exercise programme is effective in preventing hamstring injuries in male amateur soccer players and has a good compliance
It is expected that approximately 50% of the emergency room visits of COPD patients are not directly related to COPD.
Structured cultural sensitive pre-Ramadan education helps people with diabetes who choose to participate in Ramadan fasting to experience a safer Ramadan period. Pre-Ramadan education reduces the risk of acute complications such as hypoglycemia. The…
1. The primary objective of this study is to investigate whether nocebo effects on cowhage-evoked itch can be induced by verbal suggestion. We hypothesize that the verbal suggestion that the solution applied is an ‘itch solution’ will induce higher…
1.We expect participants in the experimental condition to show a reduced gmbling behaviour 2. We expect participants in the experimental condition to show a decrease in approach bias towards gambling cues, and weaker approach implicit associations…
The objectives of this pilot are (1) to test and develop an experimental setup to determine contrast sensitivity, visual field and adaptation time at high light conditions. (2) To perform a pilot study with 10 healthy subject.
The goal of this exploratory study is to directly compare quantitative enhancement parameters (the contrast agent kinetics) between 1.0 molar Gadobutrol with and without the utilisation of a Computer Aided Detection system (CAD) in patients with…
Stimulation of the right DLPFC of alcohol dependent patients will decrease self-reported craving and recude relapse rates. Furthermore it will increase behavioral control and normalize brain activation patterns.
Varenicline reduces craving to cocaine and/or impulsivity in human cocaine users.