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Patients suffering from high risk or relapsed leukaemia or high risk MDS can only occasionally be cured with conventional chemotherapy. Allogeneic stem cell transplantation (allo-SCT) has substantially improved the outcome of such patients due to a…
We hypothesize that DM1 is accompanied by impairments in whole-body and/or muscle metabolism.
Identify biomarkers in the stratum corneum which are suitable to assess the protective effect of sunscreens in vivo.
The module “Working with parents in creating a pleasant school” positively effects the attitudes, efforts and self-efficacy of teachers, parents, students in (jointly) counteracting bullying.
It is hypothesized that chicken eggshell membrane is effective in the regeneration of cartilage and/or immunomodulation (oral tolerance), and as such positively affects pain and stiffness in joints commonly affected in arthritis
Research question: To explore if Social Network Testing (SNT) for HIV is feasible and acceptable among men having sex with men with a non-Western migration background (MSM-NW), and if it reaches those who have never tested for HIV.
Combining FOLFIRINOX chemotherapy and stereotactic radiotherapy can lead to better regional tumor control and better overall survival in patients with locally advanced pancreatic cancer.
Primary objective: To determine the safety of once daily inhalation of the recommended daily dose of tobramycin with the Akita® and the PARI-LC® Plus nebulizer in patients with CF. Systemic absorption can be used as surrogate parameter for safety.…
The prevalence of disinhibited behavior is high in institutionalized people with the behavioral variant of frontotemporal dementia. Disinhibited behavior is associated with reduced well-being of residents and is experienced as an important challenge…
The primary objective of the study is to examine whether the WhiteTeeth app used by orthodontic patients aged 12 to 16 improves oral health behavior and oral hygiene. Primary outcomes of this RCT are dental plaque levels, gingival bleeding upon…
We hypothesize that clarifying the values of patients with incurable cancer without regular treatment options will empower patients and will create more effective patient-physician communication which helps to better attune communication to the…
We hypothesize that the deformation-area curves will show an alteration in the relationship between deformation and area for the differing (pressure or volume related) cardiovascular diseases
We hypothesize that approximately 2/3 of venous resections are justified by tumor invasion. Future studies on (intraoperative) imaging might help increase the number of justified venous resection. The prognostic value of depth of invasion will help…
A one-day-visit systematic assessment in a specialized severe asthma centre contributes to improvement in asthma control, quality of life and healthcare utilization.
this study will contribute to the implementation of shared decision making in the field of hand therapy, by mapping experiences with the application of shared decision making in current practice and by getting insight information in needs and…