1365 resultaten
The main objectives of this study are: • To gain insight into the effectiveness of the Healthy Working Approach on need for recovery in elderly care workers over one year. • To gain insight into the process of implementing the Healthy Working…
The lifestyle program will improve the quality of life and lifestyle behavior, and will decrease the healthcare utlization, comorbidity and cancer recurrence rates.
We hypothesise that standard anaesthetic management guided by mitoPO2 monitoring to optimise tissue oxygenation, using conventional measures, results in higher tPO2 during surgery and, therefore, a higher mean mitoPO2 over time.
Based on previous studies, we will expect that ambroxol improves neurological manifestations in patients with GD3.
We hypothesize there is a difference in CPM between the protocols
Wij stellen de hypothese dat een ontstekingsremmend voedingspatroon (AIDP) een gunstig effect heeft op het darmmicrobioom (diversiteit en permeabiliteit), waardoor het globaal functioneren (gemeten met Outcome Questionnaire 45, OQ-45) en de…
We hypothesize that PARP inhibitors can potentiate radiation-induced tumor cell death in patients treated with PRRT. To determine the maximin tolerated dose (MTD) of this combination, a phase 1 dose-escalation study is needed.
• There is no difference in number of bonding failures between the direct and indirect bracket bonding methods • Patients favour indirect bracket bonding over direct bracket bonding • Brackets bonded with the indirect bracket bonding will have less…
Short hydration during cisplatin chemo radiation is significantly more effective than long hydration in preventing acute kidney injury
The primary research questions are: 1. To what extent does a 4 week ReHab-TOAT regime lead to improvement of arm function in chronic stroke patients with either a severely or moderately affected arm-hand? 2. To what extent is any improvement of arm…
Blue light glasses can manipulate (i.e., inhibite) body melatonine production to re-adjust the circadian rhythm of shift workers, thereby having the potential to enhance viglance, cognitive function, and positive mood during night shift work.
We hypothesize that PHA-022121 will be more effective in both the treatment and prophylaxis of acute angioedema attacks in patients with acquired C1-inhibitor deficiency when compared to placebo.
Primary Objective: 1.To investigate whether daily electrical stimulation of gluteal and hamstring muscles combined with usual care is more effective in reducing recurrences of PUs than only usual care in individuals with chronic SCI, who often have…
We hypothesize that there will be a significant difference in anterior translation of the humeral head between patients and healthy objects. Secondly we hypothesize that the inter- and intra-rater reliability of the HHC test will be fair to good.…
Metabolic syndrome is a cluster of conditions that are associated with insulin resistance, hyperinsulinemia and type 2 diabetes (T2D). Pathophysiological conditions characterized by insulin resistance and hyperinsulinemia can lead to several, often…
The primary objective is to investigate the effectiveness of a personalized 2-year multidomain lifestyle intervention on cognitive performance in older adults at risk of cognitive decline.
The hypothesize is, that treatment with induction chemotherapy will lead to a 15% increase of the R0 resection rate compared to treatment with neoadjuvant chemoradiotherapy and surgery alone.
European randomised controlled multi-centred implementation trial amongst 24,000 individuals, at high risk for developing lung cancer, evaluating whether it is safe to have risk-based less intensive screening intervals after a negative baseline CT.
Deferiprone rescues oligodendrocytes in children with PMD and leads to improved myelination and motor function.
We hyopthesize that in SCCH patients 3-monthly pamidronate decreases locally increased bone turnover (measured by Na18F-PET scans) and thereby decreases pain, and leads to improvement in shoulder girdle function, quality of life, physical and work…