1101 resultaten
We hypothesize that PARP inhibitors can potentiate radiation-induced tumor cell death in patients treated with PRRT. To determine the maximin tolerated dose (MTD) of this combination, a phase 1 dose-escalation study is needed.
Postoperative pain management by using either regional continuous PVB or single shot ICNB is non-inferior to TEA regarding pain in patients undergoing thoracoscopic anatomical lung resection. Regarding QoR after surgery the unilateral regional…
- Six weeks of ESM combined with personalized feedback sessions, compared with treatment as usual (TAU), leads to a stronger reduction in fatigue symptoms (primary outcome clinical effectiveness). - This intervention also leads to improvements in…
Semi-structured interview study to get insight in parents’ experiences of daily use of a stander in young children with cerebral palsy to prevent hip dislocation. In addition, data will be used to identify barriers and facilitators to improve future…
Determination of preoperative cell-free DNA and circulating tumor cells alone or in combination with each other in peripheral blood of patients with colorectal liver metastases can discriminate between patients who have a recurrence of metastatic…
The hypothesis is that a single course of 12Gy preoperative radiotherapy may lead to sufficient fibrosis in a small (4cm) targeted area of pancreatic tissue where the anastomosis with either the jejunum will be created, thereby reducing the risk of…
patients with a history of drug allergies carry more HLA risk alleles than patients without drug allergies.
The goal of EEG4STROKE is to test a device that enables paramedics to accurately diagnose patients with suspected stroke on site (in the ambulance or living room of the patient). EEG4STROKE will integrate hardware and software to triage stroke…
Diaphragm thickness is constant throughout the zone of apposition in craniotomy-caudal direction
Het hoofddoel van dit onderzoek is om het effect van een chirurgische correctie van een spits-varus voet ten opzichte van conservatieve behandeling op het behalen van persoonlijke doelen te evalueren. Daarnaast wordt het effect van een chirurgische…
The Trammpolin® medial meniscus prosthesis is intended to restore the function of the natural meniscus to provide unicompartmental pain relief in the meniscus-deficient knee and redistributes the loads transmitted across the knee joint. The ability…
The aim of the present study is: can a single case observation of two distinct phases during systole (laminar and turbulent) be confirmed in other patients with aorta stenosis?
We hypothesize that the combination of LFPs (recorded with implanted DBS electrodes) and resting state fMRI and 64-channel EEG can provide insight in the thalamocortical coupling and other brain circuits involved in the disturbed brain dynamics in…
Group Schema Therapy is more effective and more cost-effective than Individual Schema Therapy and than Treatment-as-Usual
Primary hypothesis: An extension of the psychotherapeutic treatment concept by animal-assisted group therapy (plus treatment as usual / TAU) lowers depressive symptomatology, possibly via increases in patients' experience of self-efficacy and…
The number of flares during tapering of biologicals in patient with rheumatoid arthritis can be reduced by using a dynamic flare prediction model
A drop-out rate of 50% at 1 year follow up is anticipated.
We hypothesise that HCP provides reproducible and accurate measurements of LV volume changes during different CRT pacing settings which are comparable with invasive conductance catheter measurements.
Powerspiral enteroscopy provides an effective endoscopic procedure. Total small-bowel enteroscopy can be achieved, in one or two sessions, even in the presence of altered gastro-intestinal anatomy. It provides a great reduction of the enteroscopy…
No hypothesis due to the explorative character of the study