812 resultaten
To prospectively study if patients carrying clinically relevant DPYD variants (DPYD*2A, c.2846A>T, c.1236G>A/HapB3, c.1679T>G) are more at risk for developing moderate/severe vesicles or bullae with 5-FU cream.
We hypothesize that in many patients there will be an inconsistency between administrating medication and registration in the EHR of more than 15 minutes. Making retrospective studies drawing conclusions on data from the EHR less reliable.
Reducing the dose in the setting of therapeutic drug monitoring (TDM) does not affect clinical disease activity and safety, while it will reduce costs.
The different processing of formulas will have an effect on stool characteristics such as consistency, frequency, amount and colour.
The combination of PARP and PD-L1 inhibition has a synergistic effect and will result in progression free survival improvement.
PAE results in significant IPSS reduction
Delayed umbilical cord clamping (DCC) can improve neonatal transition in term of heart rate and respiratory condition and stimulate placental transfusion with higher concentrations of hemoglobin and hematocrit post-partum. The possible maternal side…
LEND surgery is a (cost)-effective treatment option for patients with Diabetes and lower extremity compression neuropathy, compared to conventional (non-surgical) care.
Chemodenervation by lidocaine of the m. vastus intermedius and the m. rectus femoris improves gait pattern in stroke patients presenting a stiff knee gait.
For over a decade, adults suffering from Raynaud’s phenomenon secondary to systemic sclerosis, have been supplied with textiles (gloves, socks, shirts and pants) which contain silver fibres. In general, patients state to experience benefit from…
A switch to thrombininhibitor dabigatran or addition of tranexamic acid to the factor Xa inhibitor may be effective in women who experience heavy menstrual bleeding during anticoagulant treatment with factor Xa inhibitors.
Functional treatment with a Lucerne cast leads to less stiffness, better functional outcome, earlier return to work and concomitant lower costs compared to immobilization with a forearm cast in patients with metacarpal fractures 2-4 and 5th MCFs (…
• H1: The use of the ABC tool leads to more self-management • H2: The ABC tool will be more effective in patients with better baseline self-management abilities
The PainCart is a test battery of human evoked pain models which is able to measure biomarkers for nociceptive and inflammatory pain at early stages of drug development in healthy volunteers. As such, this method can be utilized as a decision making…
Current frailty screening practice can be improved in specialized burn care
the Aeonose is able to discriminate between patients with Barrett’s esophagus versus patients without a diagnosis of Barrett’s esophagus.
A 16-week multidisciplinary lifestyle program, based on (1) a WFPD, (2) exercise and (3) stress management H0: has no effect on the WOMAC in patients with hip- and/or knee osteoarthritis and metabolic syndrome, in comparison with usual care. H1:…
K-wire fixation followed by direct mobilization leads to better functional outcome, earlier return to work, less re-operations and concomitant lower costs compared to open reposition and internal fixation with direct mobilization in adult patients…
Perturbation-based gait training improves dynamic stability and reactive responses in daily life in older adults. Therefore, the risk of falling can be reduce by training.